High-throughput scientist

Serova; San Francisco (CA); On-site; USD 110,000 - 170,000; Full time

Job summary

Serova in San Francisco is seeking a bench scientist to accelerate cancer vaccine target discovery. You will run high-throughput peptide and TCR screens, design plate-based and pooled assays, and automate workflows with liquid handlers, collaborating closely with computational scientists and ML models.

The role emphasizes reproducibility, library- and plate-centric thinking, and the ability to relocate to the San Francisco Bay Area if needed.

Qualifications

• Advanced degree in immunology or related field with hands-on screening experience.
• Experience with high-throughput screening and library approaches is required.
• Ability to work with computational scientists and ML models is preferred.

Responsibilities

• Run high-throughput screening of libraries to identify targets for each patient.
• Execute peptide, peptide-HLA, and TCR screening at scale.
• Design screen layouts and keep experiments reproducible.
• Automate screening workflows on liquid handling systems.
• Provide clean data to the computational team for model training.

Skills

High-throughput screening

Liquid handling robots

Data cleaning

Collaboration with ML models

Education

MSc/PhD in Immunology or related field

Tools

Plate-based assays

Peptide/pHLA/TCR screening platforms

Laboratory automation

Job description

About Serova

Serova builds personalized cancer vaccines. Each vaccine is made for the individual patient from their own samples and given in partnership with their treating physician. Because every patient gets their own vaccine, we screen a huge number of candidate targets, and speed matters.

The role

Every patient gets their own vaccine, so we need to test a lot of targets fast. You'll run our high-throughput peptide and TCR screening: testing large libraries of peptides, peptide-HLA complexes and TCRs to find what works for each patient.

What you'll do

• Run binder screening: peptide and peptide-HLA binders at scale
• Run TCR screening across large libraries
• Design plate-based and pooled screens, and keep them reproducible
• Automate screens on liquid handlers
• Hand clean data to our computational team to train our models

Who you are

• A bench scientist who thinks in libraries and plates, not single experiments
• Comfortable working alongside computational people and ML models
• Early career is fine if your screening experience is real
• High agency, friendly and low ego

Requirements

• An MSc or PhD in immunology, protein engineering, bioengineering or similar
• Hands-on high-throughput screening: display libraries, pooled screens or plate-based assays
• Based in the San Francisco Bay Area, or willing to relocate
• Authorized to work in the US, or a realistic path to get there

What will make you stand out

• Peptide, peptide-HLA or TCR screening
• Experience at a high-throughput biology startup, such as a protein testing or screening platformDisplay and library methods: yeast, phage or mammalian display, pooled screens
• Computational fluency: structural bioinformatics, or ML on immune repertoires
• You run liquid handlers and write your own robot methods
• Training in a strong systems or synthetic immunology lab

Details

• Location: San Francisco
• Type: Full-time