Research Associate – Protein Science

ALLTECH CONSULTING SVC INC; California (MO); On-site; USD 50,000 - 70,000; Full time

Job summary

A biotech company is seeking a Research Associate in California to be responsible for producing and purifying antibodies and related therapeutic proteins. Candidates should have a BS in biology or a related field, and hands-on experience with cloning, mammalian cell cultures, and aseptic techniques is crucial. This role is ideal for individuals who thrive in a fast-paced environment and possess strong communication skills.

Qualifications

• Hands-on experience with cloning techniques is required.
• Experience with protein characterization assays such as SDS-PAGE and SEC-HPLC is required.
• Experience in a research lab environment is required.

Responsibilities

• Responsible for the production and purification of antibodies and related therapeutic proteins.
• Support protein production by small- and large-scale transient transfection.

Skills

Cloning

Mammalian cell cultures

Aseptic techniques

Vi-CELL

Octet

HPLC

Protein purification techniques

Education

BS in biology, biochemistry, or a related discipline

Tools

AKTA instruments

Job description

We are seeking a Research Associate who will be responsible for the production and purification of antibodies and related therapeutic proteins. This position is based in Emeryville, CA, 94608 in the EmeryStation West campus, at 5959 Horton St., easily accessible by BART / EmeryGoRound, AMTRAK, or car (with private, secured, on-site parking provided.)

The Company’s Biologics Emeryville, CA site, formerly the startup company Redwood Bioscience, has developed a proprietary approach for site‑specific bioconjugation to produce next‑generation ADCs. This technology, termed SMARTag®, is based on use of the aldehyde‑tag site‑specific protein modification technology and Company’s novel conjugation chemistry and proprietary, stable linkers. SMARTag® is a clinical‑stage technology, with its first ADC—TRPH‑222—in Phase 1 clinical trials.

The Company’s Biologics Emeryville site comprises a close‑knit team of scientists working cross‑functionally with each other to nimbly achieve our goals and milestones. We are a research site, working to develop therapeutic ADC drug candidates for clinical testing. We also continuously strive to improve and expand our technology platform. The team has a focus on publishing results and contributing to the exciting and dynamic field of bioconjugation and drug conjugates.

Our Pharma Solutions is the leading provider of pharmaceutical development services, drug delivery technologies, manufacturing, packaging, and product commercialization services to the global pharmaceutical and biotechnology industry. We employ over 15,000 people in more than 40 facilities worldwide with reported annual revenues of approximately $1.8 billion. At our Company, we take pride in providing a shared commitment to build employee capability, and foster a culture of inclusion, where talent and potential are unleashed, and where employees are committed and engaged to achieve results.

We are committed to a Patient First culture through excellence in quality and compliance, and to the safety of every patient, consumer and ouremployee.

Key Competencies:

• Hands‑on experience with cloning, mammalian cell cultures and aseptic techniques are required.
• Cloning (Gibson assembly), Mini, Maxi, Giga preps, DNA sequence confirmation
• Support the protein production by small- and large‑scale transient transfection.
• Experience with Vi‑CELL , Octet and HPLC is required.
• Experience in protein characterization assays such as concentration, endotoxin measurement, SDS‑PAGE and SEC‑HPLC is required.
• Experience in antibodies and other protein purification techniques is preferred.
• Experience using AKTA instruments is preferred.

Requirements:

• BS in biology, biochemistry, or a related discipline. BS with 0+ years of relevant experience.
• >1 year of experience in a research lab environment, preferably including work under sterile conditions

Personal Characteristics:

The successful candidate must possess the following characteristics:

• A high degree of personal and professional integrity
• Strong interpersonal and communication skills
• Ability to deliver high quality results
• Thrives in a fast‑paced environment
• Can adjust to changing situations, providing ideas and solutions