Heme, Research Fellow

Scorpion Therapeutics; Boston (MA); On-site; USD 350,000 - 550,000; Full time

Job summary

Scorpion Therapeutics seeks a senior leader to drive lead discovery and translational research for in vivo gene editing therapies targeting hemoglobinopathies. The role spans target selection, preclinical work, IND-enabling studies, and Phase 1/2 trial readiness.

Responsibilities include shaping scientific strategy, guiding in vitro/ex vivo/in vivo studies, supporting candidate optimization, and leading cross-functional teams toward nomination of a development candidate.

Qualifications

• MD or PhD with 11+ years in biotech/pharma research and drug development.
• Expertise in translational science and disease biology.
• Experience with cell/gene therapy and genome editing.

Responsibilities

• Lead in vivo gene editing programs for hemoglobinopathies.
• Direct target selection, preclinical, IND-enabling studies, and early clinical planning.
• Guide cross-functional teams to nominate development candidates and shape strategy.

Skills

Drug development

Translational science

Disease biology

Cell therapy

Genome editing

GMP/GLP knowledge

Education

MD/PhD

Job description

Role

Lead drug discovery and translational research for in vivo gene editing therapies targeting hemoglobinopathies, with responsibilities spanning target selection, preclinical, IND-enabling studies, and Phase 1/2 trials. Responsibilities include shaping scientific strategy, guiding in vitro/ex vivo/in vivo studies, supporting target and candidate optimization, and leading cross-functional teams toward development candidate nomination.

Requirements

• MD and/or PhD with 11+ years in academic, biotech, or pharma research, expertise in drug development, translational science, and disease biology, with experience in cell/gene therapy and genome editing.

Preferred

• Direct hemoglobinopathy experience (e.g., sickle cell, thalassemia), familiarity with delivery systems, editing efficiency, HSC biology, regulatory pathways (FDA/EMA), and GCP.

High-Value

• Hemoglobinopathies, gene editing, in vivo pharmacology, IND-enabling programs, clinical translation, and leadership in matrixed environments.

Work setup

On-site, five days/week, with ad hoc flexibility.