Head of Platform Technologies MSAT Recombinant Mammalian Drug Substance CoE

Sanofi; Framingham (MA); Hybrid; USD 250,000 - 350,000; Full time

Benefits offered by this job

High-quality healthcare

Wellness programs

Parental leave (14 weeks)

Job summary

Sanofi in Framingham, MA is seeking a Head of Platform Technologies for the MSAT Recombinant Mammalian CoE. Lead a team advancing perfusion cell culture, continuous purification, PAT, and smart manufacturing to enable commercial programs.

You will collaborate with upstream, downstream, and analytics teams, harmonize technology transfer, and drive global MSAT innovation initiatives while mentoring staff and ensuring scientific excellence. Hybrid onsite schedule required.

Qualifications

• PhD preferred; Master’s degree required.
• 10+ years of experience in biopharmaceutical industry.
• 5+ years in biologics drug substance process development or manufacturing support.

Responsibilities

• Lead evaluation of next-generation platform technologies (perfusion cell culture, continuous purification, PAT, smart manufacturing).
• Define development data package requirements and readiness for scale-up and tech transfer.
• Align platform initiatives with program goals, robustness, and yield improvements.
• Establish and maintain innovation infrastructures within the COE.
• Collaborate with upstream/downstream/analytical teams to advance digitization and automation.
• Build and maintain lab and pilot-scale capabilities.
• Manage relationships with external partners and vendors.
• Coordinate activities with MSAT, R&D, and Global Procurement to support programs.
• Drive cross-platform innovation initiatives within MSAT.

Skills

Biopharma industry

Bioprocess development

Leadership

Project management

English fluency

Education

Master's degree

PhD

Job description

Head of Platform Technologies, MSAT Recombinant Mammalian Drug Substance CoE | Location: Framingham, MA

Sanofi Global MSAT (Manufacturing Sciences, Analytics, and Technology) acts as a crucial link between our R&D and Manufacturing facilities, playing a vital role in securing the present portfolio and delivering future launches of high-quality and innovative drugs and vaccines. By driving its own transformation, Global MSAT fulfils an important function by providing day-to-day Manufacturing Support, focusing on technical and process aspects, effective Life Cycle Management, process robustness enhancement, and yield improvement to optimize performance. Join our global network and contribute to the launch of 3 to 5 new products annually across various modalities, enabling us to reach and serve more patients and communities. Collaborate with a team of talented and passionate international experts, scientists, and project leaders who are dedicated to inventing, designing, and implementing cutting-edge industrial chemical and biological processes, analytical methods, and process modelling, all in support of Sanofi’s best-in‑class ambition. The Head of Platform Technologies will lead a dynamic team of Subject Matter Experts within the MSAT Recombinant Mammalian Center of Excellence (CoE), located at Sanofi’s Massachusetts Framingham Bio-Campus. This team is responsible for establishing state-of-the-art innovation laboratory infrastructures and enabling next-generation platform technologies, including perfusion cell culture and continuous purification processes. This senior leadership role will support implementation strategies for commercial programs by collaborating closely with R&D, Manufacturing, and external partners. The team will also spearhead global MSAT innovation initiatives across platforms in partnership with other MSAT groups, while representing MSAT’s scientific leadership and excellence in both internal and external forums. We deliver 4.3 billion healthcare solutions to people every year, thanks to the flawless planning and meticulous eye for detail of our Manufacturing & Supply teams. With your talent and ambition, we can do even more to protect people from infectious diseases and bring hope to patients and their families. We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system and innovative pipeline enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve lives. *Hybrid Schedule - 3 days per week onsite- required.

Main Responsibilities

• Lead the evaluation of Sanofi’s next-generation platform technologies including perfusion cell culture, continuous purification, advanced Process Analytical Technology (PAT), smart manufacturing, and emerging novel process chemistries.
• Develop the MSAT position on development data package requirements, at-scale operational readiness, transferability, lab-scale model expectations, and MSAT training and expertise needs.
• Ensure alignment of platform-technology initiatives with broader organizational objectives such as 2nd-generation program development, process robustness, and yield improvement.
• Establish and maintain cutting-edge innovation laboratory infrastructures within the COE.
• Partner with upstream, downstream, and analytical teams to advance lab digitization and automation.
• Build additional laboratory and pilot-scale capabilities that embody Sanofi’s smart-lab future concept.
• Build and maintain strategic relationships with external partners and vendors.
• Oversee multiple collaboration projects with external suppliers to support manufacturing investigations, process development, raw material characterization, novel equipment and capability assessment, and co-development of new technologies.
• Coordinate these activities seamlessly with MSAT, R&D, and Global Procurement functions.
• Drive global MSAT innovation initiatives in collaboration with other technology platforms (Vaccines, Drug Product, Microbial).
• Promote knowledge sharing and best-practice adoption across teams.
• Represent MSAT’s scientific excellence in internal forums (smart factory, digital transformation, eco-design, efficiency) and external forums (Bio-Industry forums, biomanufacturing conferences). Strengthening Sanofi’s reputation as a leader in biopharmaceutical manufacturing innovation.
• Contribute to CoE activities by providing SME input and technical guidance for laboratory work, commercial program life cycle management, and technology transfers.
• Collaborate effectively with both local and network cross-function teams (e.g. lab, manufacturing, quality, regulatory, business etc.) as needed.
• Mentor and develop team members, fostering their professional growth and technical expertise, while ensuring a diverse technical background and comprehensive skillset coverage for drug substance processes as part of CoE strategic workforce planning.

About You

• PhD degree in Chemical/Biological/ Sciences/Engineering - preferred.
• Master's degree - required.
• 10+ years of experience related to biopharmaceutical industry - required.
• 5+ years of hands-on experience in biologics drug substance process development, technology development or manufacturing support - required.
• Demonstrated experience leading bioprocess and biomanufacturing innovation initiatives from concept through implementation.
• Deep knowledge of bioprocess development and operations (e.g., upstream, downstream, drug-substance stability).
• Familiarity with laboratory, pilot-scale, and large-scale manufacturing operations.
• Process knowledge across multiple modalities (e.g. mAbs, small protein and peptide, bioconjugates, nucleotides, Gene/cell therapy, organic chemistry etc.).
• Prior experience of managing suppliers, contractor manufacturing or contract research partners.
• Excellent scientific background and effective communication skills.
• Demonstrated ability to manage and prioritize multiple projects and consistently meet deadlines.
• Highly motivated individual, with the ability to work independently as well as within cross‑functional and cross‑site teams.
• Oral and written fluency in English.

Why choose us? Bring the miracles of science to life alongside a supportive, future-focused team. Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally. Enjoy a thoughtful, well‑crafted rewards package that recognizes your contribution and amplifies your impact. Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention andwellness programs and at least 14 weeks’ gender-neutral parental leave. Shape the future of medicine and vaccine delivery with cutting‑edge technology, ensuring seamless launches and a resilient global supply. Power industry‑leading performance by leveraging digital, data, and AI‑driven innovation at speed and scale Transform lives worldwide by delivering life‑changing treatments anywhere, anytime.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

North America Applicants Only The salary range for this position is: $178,500.00 - $257,833.33 All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

We are an R&D-driven, AI-powered biopharma company committed to improving people’s lives and creating compelling growth. Our team is guided by one purpose: we chase the miracles of science to improve people’s lives. We want to build a healthier, more resilient world, and turn the impossible into the possible by discovering, developing, and delivering medicines and vaccines for millions of people around the world. Discover more about us visiting www.sanofi.com or via our movie We are Sanofi Start a career that makes a difference. Reinvention is in our DNA. It’s what drove our evolution from a small French enterprise to one of the world’s leading biopharma companies. Whether it’s using AI to shorten drug‑discovery times or building trust in healthcare, you could be helping our teams make life better for patients, partners, and communities. This is where you grow your career. We open the door for you to explore new opportunities, push your limits, and connect with people who are driven by a shared purpose: we chase the miracles of science to improve people’s lives.