Senior Associate Scientist - Drug Product Development

Sanofi; Cambridge (MA); On-site; USD 110,000 - 140,000; Full time

Benefits offered by this job

Health benefits

Wellbeing programs

Parental leave

Job summary

Sanofi in Cambridge, MA is seeking a Senior Associate Scientist in Drug Product Development to advance oral solid dosage formulations from preclinical to GMP manufacturing readiness, collaborating across CMC teams and external partners.

You will design experiments, execute DoE, and contribute to scale-up; perform dissolution and solubility studies, develop enabling formulations, and maintain rigorous documentation and safety practices in a fast-paced, cross-functional environment.

Qualifications

• 4+ years (Bachelor) or 2+ years (Master) hands-on pharmaceutical product/process development experience.
• Experience with oral solid dosage formulation (tablets/capsules).
• Experience running dissolution studies (USP2/USP4/USP7) and/or Pion equipment.
• Solubility testing experience.
• Industry experience preferred; academic work is acceptable with industry relevance.

Responsibilities

• Support the design and development of oral solid dosage formulations (tablets, capsules, granules) for preclinical and clinical programs
• Execute formulation studies including excipient compatibility testing, prototype development, and formulation optimization under guidance
• Contribute to conventional and enabling formulations (e.g., amorphous dispersions) to address bioavailability challenges
• Support formulation and process development activities, including granulation, blending, compression/tableting, and encapsulation
• Assist in applying DoE methodologies to optimize formulation and process parameters
• Collaborate within the CMC team and support defined deliverables and milestones
• Work with Analytical, Biopharm, Quality, and Regulatory colleagues to align development strategies
• Support Research interactions to evaluate molecular attributes relevant to drug delivery and formulation design
• Author and review technical reports, batch records, and supporting documentation
• Ensure documentation is accurate, complete, and compliant
• Maintain awareness of current scientific literature
• Plan standard and moderately complex experiments with limited guidance

Skills

Oral solid dosage

Dissolution studies

Solubility testing

DoE methodologies

Scale-up

Technology transfer

Cross-functional teamwork

Analytical mindset

Communication skills

Education

Bachelor's in Pharmaceutical Sciences

Master's in related field

Tools

Tablet presses

Granulation equipment

Capsule filling

Coating equipment

Dissolution apparatus

Job description

Job Title: Senior Associate Scientist Drug Product Development

• Location: Cambridge, MA

About the Job:

This position supports the development of oral solid dosage formulations for small molecule drug products. The successful candidate will contribute to the design, development, and optimization of preclinical formulations (conventional and enabling) and clinical solid oral dosage forms (tablet and capsule), from early-stage development through scale-up and technology transfer to GMP manufacturing. Working under the guidance of senior team members and in close collaboration with cross-functional CMC teams, the candidate will apply hands-on laboratory skills and foundational scientific knowledge to help advance drug candidates into clinical development.

Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions.

About Sanofi:

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

Main Responsibilities:

• Support the design and development of oral solid dosage formulations (tablets, capsules, granules) for preclinical and clinical programs

• Execute formulation studies including excipient compatibility testing, prototype development, and formulation optimization under guidance

• Contribute to the development of conventional and enabling formulations (e.g., amorphous dispersions) to help address bioavailability challenges

• Support formulation and process development activities, including granulation (wet and dry), blending, compression/tableting, and encapsulation

• Assist in applying DoE methodologies to optimize formulation and process parameters, with guidance from senior scientists

• Collaborate within the CMC team as a contributing team member, supporting defined deliverables and milestones

• Work with Analytical, Biopharm, Quality, and Regulatory colleagues to support alignment on development strategies

• Support Research team interactions to help evaluate molecular attributes relevant to drug delivery and formulation design

• Author and review technical reports, batch records, and supporting documentation with guidance from senior staff

• Ensure all documentation is accurate, complete, and compliant with requirements

• Maintain awareness of current scientific literature relevant to assigned projects

• Makes decisions that may require extrapolation of technical knowledge. Decisions generally impact own work and may impact the work group or project team.

• Independently plans standard and moderately complex experiments with relevant controls, with limited guidance from supervisor or subject matter experts. Able to plan and manage a set of concurrent experiments.

• Individual contributor. Understands the responsibilities of being a team member and adheres to appropriate documentation and safety practices.

• Presents internally within the functional group and to other local functions. May present to project or cross-functional teams as appropriate.

• Organizes own daily work to meet deadlines. Contributes to team objectives and short-term operational goals under supervision.

About You:

Basic Qualifications

Education:

• Bachelor's degree OR Master's degree in Pharmaceutical Sciences, Chemistry, Chemical Engineering, Biomedical Engineering, Materials Science, Food Science, or a related life science/scientific/engineering discipline

Experience:

• 4+ years (Bachelor's holders) OR 2+ years (Master's holders) of hands-on experience in product or process development in a pharmaceutical, laboratory or related environment

• Experience with oral solid dosage formulation (tablets and/or capsules)

• Experience running dissolution studies using standard apparatus (USP2, USP4, USP7) and/or Pion equipment

• Solubility testing experience

• Academic or research experience will be considered but industry experience is required

Preferred Qualifications

• Experience with enabling formulations such as amorphous solid dispersions, nanosuspensions, or lipid-based formulations

• Excipient compatibility testing and formulation screening experience

• Hands-on experience with tablet presses (rotary and/or single-station)

• Experience with granulation equipment (high-shear, fluid bed, and/or roller compaction)

• Experience with capsule filling machines and/or coating equipment

• Working knowledge of powder characterization techniques

• Familiarity with Design of Experiments (DoE) methodologies

• Exposure to process scale-up and technology transfer activities

• Experience working with external manufacturing or research partners

• Strong problem-solving skills and scientific curiosity

• Effective oral and written communication skills

• Ability to work collaboratively in a cross-functional team environment

• Good organizational skills with the ability to manage multiple tasks and projects simultaneously

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team.

• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

• Help improve the lives of millions of people globally by making drug development quicker and more effective.

• Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.

• Achieve genuine work-life balance in a supportive R&D environment.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and affirmative action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.