Head of Biotech Facilities, Lab Ops & EHS

Olema Oncology; San Francisco (CA); On-site; USD 210,000 - 225,000; Full time

Job summary

Olema Oncology is seeking a Director of Facilities, Laboratory Operations and EHS to provide strategic leadership across multiple sites in San Francisco. You will own day-to-day facility and lab operations, lead real estate strategy, manage capital projects, ensure safety and compliance, and partner with Research, IT, Real Estate, Finance and executive leadership.

Requires 12+ years in facilities and lab ops, Bachelor’s degree, CSP/SFM preferred; 15% travel.

Qualifications

• Bachelor’s degree required.
• 12+ years in facilities and lab operations.
• Experience with BSL-2 labs and lab builds.
• Proven ownership of EHS programs and regulatory interactions.

Responsibilities

• Oversee day-to-day facility operations across multiple sites, ensuring uptime, safety, and compliance.
• Lead all facilities operations and physical infrastructure activities, including site readiness, expansions, and relocations.
• Own Real Estate strategy: leases, transitions, expansions, consolidations, exits.
• Direct laboratory and office buildouts from programming through occupancy, including permitting and commissioning.
• Manage capital projects in active lab environments with risk management and continual operation.
• Develop and enforce facilities standards, SOPs, and security programs (access, alarms, vendor oversight).
• Control budgets and forecasts for facilities; monitor spend and cost accountability.
• Lead emergency planning and response across all facilities; ensure continuity of scientific operations.
• Oversee shipping/receiving and hazardous materials handling; ensure regulatory compliance.

Skills

Facilities leadership

Laboratory operations

EHS programs

Project management

Cross-functional collaboration

Education

Bachelor's Degree

Job description

Olema Oncology is seeking a Director of Facilities, Laboratory Operations and EHS to provide strategic leadership across multiple sites in San Francisco. You will own day-to-day facility and lab operations, lead real estate strategy, manage capital projects, ensure safety and compliance, and partner with Research, IT, Real Estate, Finance and executive leadership.

Requires 12+ years in facilities and lab ops, Bachelor’s degree, CSP/SFM preferred; 15% travel.