Group Lead, Immunology

NewLimit; South San Francisco (CA); On-site; USD 180,000 - 240,000; Full time

Benefits offered by this job

Health insurance

Dental insurance

Vision insurance

401(k) with company match

Paid parental leave

PTO 20 days

On-site meals

Job summary

NewLimit is seeking an immunologist to lead our Immunology team, advancing reprogramming medicines for aging-related immune dysfunction. You will steer discovery and development, mentor scientists, and collaborate across Epigenetic Editing, Single Cell Tech, and Predictive Modeling to drive candidate selection and progression.

You will shape our product development strategy, contribute to platform decisions, and help build a world-class immunology program at a cutting-edge biotechnology company

Qualifications

• Ph.D. in cell biology or immunology, or comparable industry experience.
• Experience leading a team with direct reports.
• Experience with therapeutics development in immunology, infectious disease, or inflammatory disease settings.
• Deep knowledge of immunology and lymphocyte biology.
• Nice to have: direct T cell biology experience with functional assays and pre-clinical models.
• Nice to have: experience with in vivo nucleic acid delivery and pooled screening techniques.

Responsibilities

• Lead a team of Scientists and Research Associates to develop reprogramming therapies.
• Develop functional assays and pre-clinical models for inflammatory and infectious disease indications.
• Evaluate reprogramming payloads using functional assays and pre-clinical models to validate payloads, select leads, and progress pre-clinical candidates.
• Collaborate with Single Cell Technology, Epigenetic Editing, and Predictive Modeling teams to design, build, and test reprogramming interventions.
• Contribute to NewLimit’s product development decisions, company-wide goals, and technology platform; be a key part of building the company and your team.
• Contribute to day-to-day execution alongside your team; everyone executes at NewLimit.

Skills

Team leadership

Immunology expertise

Therapeutics development

Lymphocyte biology

T cell biology

Computational biology

Education

Ph.D. in cell biology or immunology

Job description

NewLimit is a biotechnology company working to radically extend human healthspan. We’re developing medicines to treat age-related diseases by reprogramming the epigenome, a new therapeutic mechanism to restore regenerative potential in aged and diseased cells. We leverage functional genomics, pooled perturbation screening, and machine learning models to unravel the biology of epigenetic aging and disease using experiments of unprecedented scale.

Position

NewLimit is seeking an immunologist with leadership experience in therapeutics to lead our Immunology team. Our Immunology program is developing reprogramming medicines to restore youthful function in aged T cells for the treatment of inflammatory & infectious diseases with a strong emphasis on T cell and regulatory T cell (Treg) biology.

What you’ll do

As the leader of Immunology team, you will:

• Lead a team of Scientists and Research Associates to develop reprogramming therapies
• Develop functional assays and pre-clinical models for inflammatory and infectious disease indications
• Evaluate reprogramming payloads using functional assays & pre-clinical models to validate payloads, select leads, and progress pre-clinical candidates
• Collaborate with our Single Cell Technology, Epigenetic Editing, and Predictive Modeling teams to design, build, and test reprogramming interventions
• Contribute to NewLimit’s product development decisions, company-wide goals, and technology platform. You will be a key part of building the company in addition to your team.
• Contribute to day-to-day execution alongside your team. Everyone Executes at NewLimit.

Requirements

• Ph.D. in cell biology, immunology, or a related field or comparable industry experience
• Experience leading a team and managing direct reports
• Experience with therapeutics development, ideally leading a portion of a discovery or development process in an immunology, infectious disease, or inflammatory disease setting
• Deep knowledge of immunology & lymphocyte biology

Nice to have

• Direct experience with T cell biology, including relevant functional assays, pre-clinical models, and experimental methods
• Experience with in vivo nucleic acid delivery technologies
• Experience with pooled screening and related functional genomics methods
• Strong molecular biology foundations and experience designing transgenic constructs
• Experience with iterative product development cycles (e.g. design-build-test-learn)
• Knowledge of aging biology, computational biology, and machine learning

NewLimit offers generous benefits to ensure our team can focus on our mission:

• Health, dental, and vision insurance
• 401(k) with company match
• Paid parental leave
• Industry-leading paid time off (PTO) - 20 days/year for all employees + holidays
• Meals and snacks on-site

Salary Range: $180,000 to $240,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. NewLimit offers a competitive benefits package, which includes a 401k, healthcare coverage, and 20 days of PTO. Learn more at: https://www.newlimit.com/careers *This compensation and benefits information is based on Company's good faith estimate as of the date of publication and may be modified in the future.