Global Viral Vector MSAT Lead, In Vivo Platforms

BioSpace; Raritan (NJ); On-site; USD 146,000 - 192,000; Full time

Benefits offered by this job

Medical, dental, and vision insurance

401(k) with company match

Paid parental leave

Paid time off

Job summary

Legend Biotech is seeking a Global Viral Vector MSAT Lead in Raritan, NJ. The role provides technical leadership across in vivo viral vector platforms, overseeing GMP manufacturing support from development to clinical supply and eventual scale-up.

You will own process knowledge, drive technology transfer to GMP sites and CMOs, and lead investigations, CAPAs, and CPV strategies while partnering with Process Development, Manufacturing, Quality, and Regulatory teams to enable reliable supply and

Qualifications

• Bachelor's degree in biology, engineering, or related field.
• 10+ years in MSAT, tech transfer, or process development.
• Industrial biologics CMC development or manufacturing experience.
• Experience in cell therapy commercial cGMP programs and global change management.
• Strong cross-functional collaboration and regulatory submission experience.

Responsibilities

• Lead MSAT technical support for clinical and late-stage GMP manufacturing of viral vectors for in vivo platforms.
• Own end-to-end process knowledge for assigned viral vector platforms, including upstream production, downstream purification, formulation, and fill/finish interfaces.
• Lead technology transfer of viral vector processes from Process Development into GMP manufacturing, including internal sites and external CDMOs.
• Serve as the primary MSAT technical lead for deviations, root cause investigations, risk assessments, and CAPA execution.
• Drive process characterization, control strategy development, continued process verification (CPV), and performance trending.
• Partner cross-functionally to identify and mitigate manufacturing, scale-up, and comparability risks to ensure supply continuity.
• Provide MSAT technical input to CMC regulatory submissions, health authority interactions, and inspection readiness.
• Lead, mentor, and develop a team of MSAT scientists and engineers.
• Drives justification and alignment with key partners (ie. JnJ).

Skills

MSAT Lead

Tech Transfer

Process Development

Cell Therapy

Regulatory Submissions

Cross-functional Collaboration

Education

B.S. degree

Job description

Legend Biotech is seeking a Global Viral Vector MSAT Lead in Raritan, NJ. The role provides technical leadership across in vivo viral vector platforms, overseeing GMP manufacturing support from development to clinical supply and eventual scale-up.

You will own process knowledge, drive technology transfer to GMP sites and CMOs, and lead investigations, CAPAs, and CPV strategies while partnering with Process Development, Manufacturing, Quality, and Regulatory teams to enable reliable supply and