Global Oncology Portfolio Strategy Leader

Pfizer Inc.

Cambridge (MA)

Hybrid

USD 215,000 - 358,000

Full time

5 days ago
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Job summary

Pfizer Inc. is seeking a Senior Director, Oncology Portfolio Strategy to shape long-range portfolio plans, allocate resources, and steer cross-functional initiatives across R&D, Medical, Commercial, and Regulatory groups.

You will translate scientific insights into enterprise-level recommendations and drive governance decisions. You will partner with Oncology leadership to evolve portfolio management, harness AI-enabled tools, and balance scientific opportunity with patient impact and commercial

Qualifications

  • Bachelor's degree is required.
  • 12+ years of progressive experience in pharmaceutical, biotechnology, life sciences, commercial development, portfolio strategy, business development, strategy consulting, corporate strategy, or related fields.
  • Experience in Oncology.
  • Demonstrated experience leading enterprise-level strategic initiatives and influencing significant investment decisions.
  • Strong strategic, analytical, and financial acumen, including experience evaluating risk, uncertainty, and value creation.

Responsibilities

  • Lead development and evolution of the Oncology portfolio strategy, identifying highest-value opportunities across tumor types, modalities, and platforms.
  • Develop long-range portfolio scenarios and strategic roadmaps that inform future investment priorities.
  • Assess portfolio strengths, gaps, risks, and opportunities to support proactive decision-making and resource allocation.
  • Drive portfolio-level strategic trade-off discussions balancing scientific opportunity, probability of success, patient impact, and commercial value.
  • Translate complex scientific and market dynamics into actionable portfolio recommendations for senior leadership.
  • Serve as strategic advisor to Oncology leadership on portfolio prioritization and capital allocation decisions.
  • Lead development of portfolio recommendations for governance committees and enterprise decision-making forums.
  • Establish and maintain frameworks that improve consistency, rigor, and transparency in portfolio evaluations.
  • Drive enterprise discussions on investment prioritization, development sequencing, indication expansion, and lifecycle optimization.
  • Support critical portfolio reviews and recommendation development for senior executive stakeholders.

Skills

Strategic leadership
Executive communication
Cross-functional leadership
Financial acumen
AI-enabled strategy

Education

Bachelor's degree

Job description

Pfizer Inc. is seeking a Senior Director, Oncology Portfolio Strategy to shape long-range portfolio plans, allocate resources, and steer cross-functional initiatives across R&D, Medical, Commercial, and Regulatory groups.

You will translate scientific insights into enterprise-level recommendations and drive governance decisions. You will partner with Oncology leadership to evolve portfolio management, harness AI-enabled tools, and balance scientific opportunity with patient impact and commercial

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