Global Head of Clinical Operations — Oncology Trials

Barrington James; United States; Hybrid; USD 190,000 - 280,000; Full time

Job summary

Barrington James is recruiting for a Senior Director / Head of Clinical Operations to lead a portfolio of global registrational trials across oncology. The role requires strategic and operational leadership, with a strong track record in managing CRO relationships and vendor oversight across US, EU, and Asia-Pacific sites.

The candidate will drive timelines, budgets and risk management while collaborating with Clinical Development, Regulatory, Biostatistics, and Commercial teams to scale

Qualifications

• 10+ years in clinical operations with leadership experience.
• Proven track record managing global registrational trials.
• Strong cross-functional leadership across Clinical Development, Regulatory, Biostatistics, and Commercial.
• Experience with CRO/vendor oversight across multiple regions (US/EU/APAC).

Responsibilities

• Provide strategic and operational leadership of a portfolio of global registrational trials.
• Partner cross-functionally with Clinical Development, Regulatory, Biostatistics, and Commercial teams.
• Oversee CRO relationships and vendor management across US, EU, and Asia-Pacific sites.
• Drive trial timelines, budget, and risk management for late-stage oncology programs.
• Contribute to clinical operations strategy as the company scales from single-market success to global regulatory execution.

Skills

Leadership

Global trials

Vendor oversight

Regulatory know-how

Cross-functional

Job description

Barrington James is recruiting for a Senior Director / Head of Clinical Operations to lead a portfolio of global registrational trials across oncology. The role requires strategic and operational leadership, with a strong track record in managing CRO relationships and vendor oversight across US, EU, and Asia-Pacific sites.

The candidate will drive timelines, budgets and risk management while collaborating with Clinical Development, Regulatory, Biostatistics, and Commercial teams to scale