Global Clinical Trial Manager - End-to-End Operations

Absci; United States; On-site; USD 115,000 - 150,000; Full time

Benefits offered by this job

Medical insurance

Dental insurance

401(k) with company match

Job summary

Absci is seeking an experienced Clinical Trial Manager to independently lead end-to-end execution of global Phase II-III trials. You will oversee CROs, vendors, and sites, ensuring protocols, regulatory standards, and timelines are met while maintaining high data quality and patient safety.

The role requires strong cross-functional collaboration, budget oversight, and a proactive approach to risk management in a fast-paced biotech environment.

Qualifications

• Bachelor’s degree in life sciences or related field. Advanced degree welcome but not required.
• 5+ years of direct experience in clinical trial management in pharma/biotech/CRO.
• Experience with industry sponsor settings.
• Experience in women’s health, pain, immunology, or dermatology studies a plus.
• Experience with electronic patient-reported outcomes (eCOA) systems and data quality oversight.
• Strong knowledge of GCP, FDA regulations, ICH guidelines, and regulatory filing requirements.

Responsibilities

• Independently manage operational aspects of Phase II-III global trials from startup to closeout.
• Oversee CROs and vendors to ensure alignment with study goals, regulatory standards, and timelines.
• Develop study-level operational plans, monitoring, risk management, and TMF quality control.
• Ensure robust patient recruitment and retention strategies with sites and CROs.
• Collaborate with legal and finance to manage study budgets and contracts.

Skills

Trial management

Regulatory knowledge

Vendor management

Cross-functional collaboration

Education

Bachelor’s Degree in life sciences

Advanced degree welcome

Tools

eCOA systems

TMF quality control

Job description

Absci is seeking an experienced Clinical Trial Manager to independently lead end-to-end execution of global Phase II-III trials. You will oversee CROs, vendors, and sites, ensuring protocols, regulatory standards, and timelines are met while maintaining high data quality and patient safety.

The role requires strong cross-functional collaboration, budget oversight, and a proactive approach to risk management in a fast-paced biotech environment.