Global Clinical Program Lead, Neuroimmunology

AstraZeneca plc; Cambridge (MA); On-site; USD 288,000 - 432,000; Full time

Job summary

AstraZeneca plc in Cambridge, MA seeks a Global Clinical Program Lead to own immune-reset programs from first-in-human to pivotal studies. You will define clinical strategy, steer study designs, and represent the programs with regulators and investigators.

Based in Cambridge, you will lead safety strategy, partner with regulatory, translational medicine, and commercial teams, and collaborate across global partners to accelerate delivering decisive clinical evidence.

Qualifications

• MD or equivalent with neurology or immune-mediated disease focus.
• 5+ years clinical drug development with leadership of programs or major studies.
• Experience leading regulatory submissions and health-authority interactions.
• Extensive cross-functional leadership in a matrix environment.

Responsibilities

• Define and drive clinical and scientific strategy across two programs.
• Lead endpoint strategy and trial design with speed, quality and patient focus.
• Set and oversee program safety strategy and clinical monitoring oversight.
• Own IND/CTA content and lead health-authority interactions.
• Present data-driven program updates to governance and portfolio committees.
• Engage external experts, investigators, sites, CROs and patient groups.

Skills

Clinical strategy

Study design leadership

Regulatory interactions

Global cross-functional leadership

GCP expertise

Executive communication

Travel readiness

Education

MD or equivalent degree

Postgraduate neurology/immune specialty training

Job description

AstraZeneca plc in Cambridge, MA seeks a Global Clinical Program Lead to own immune-reset programs from first-in-human to pivotal studies. You will define clinical strategy, steer study designs, and represent the programs with regulators and investigators.

Based in Cambridge, you will lead safety strategy, partner with regulatory, translational medicine, and commercial teams, and collaborate across global partners to accelerate delivering decisive clinical evidence.