Global CAR-T Program Leader — Executive Director

Initial Therapeutics, Inc.; New Jersey; On-site; USD 256,000 - 336,000; Full time

Benefits offered by this job

Medical, dental, vision insurance

401(k) with company match

Paid parental leave

Job summary

Legend Biotech in Somerset, NJ is seeking an Executive Director, Global Program Leader to oversee in vivo CAR‑T development programs, leading cross‑functional teams from IND enabling through lifecycle management.

The role requires an MD/PhD/PharmD with 10+ years in biotech, 5+ years of leadership, and deep experience in regulatory submissions and global program strategy to drive milestones in oncology cell/gene therapies.

Qualifications

• MD/PhD/PharmD or equivalent.
• 10+ years in biotech/pharmaceutical drug development.
• 5+ years leading global development programs.
• Experience advancing biologics, cell or gene therapies.
• Experience with regulatory interactions and submissions.
• Strong leadership in matrix, cross-functional environments.

Responsibilities

• Design development pathways to maximize speed to proof‑of‑concept and global approvals.
• Lead regulatory interactions and major health authority milestones.
• Oversee INDs, CTAs, BLA/MAA submissions and lifecycle management.
• Chair Global Program Teams and coordinate cross-functional execution.
• Collaborate with R&D, Regulatory, Translational Sciences, Manufacturing, Commercial, and Quality.
• Drive risk management and contingency planning across programs.
• Present strategies and milestones to senior leadership and governance committees.
• Support business development due diligence for in vivo CAR‑T technologies.

Skills

Cross-functional leadership

Strategic thinking

Executive communication

Portfolio management

Risk management

Education

MD/PhD/PharmD

Job description

Legend Biotech in Somerset, NJ is seeking an Executive Director, Global Program Leader to oversee in vivo CAR‑T development programs, leading cross‑functional teams from IND enabling through lifecycle management.

The role requires an MD/PhD/PharmD with 10+ years in biotech, 5+ years of leadership, and deep experience in regulatory submissions and global program strategy to drive milestones in oncology cell/gene therapies.