Generative Design & Optimization Advisor - Biotherapeutics

BioSpace; San Diego (CA); Sur place; USD 168 000 - 268 000; Plein temps

Avantages offerts par ce poste

401(k) plan

Pension

Vacation benefits

Well-being benefits

Résumé du poste

Lilly’s Biotechnology Center in San Diego is expanding a generative design platform to create novel antibodies and biotherapeutics. You will join a cross-disciplinary team applying AI/ML, protein engineering, automation, and structural biology to accelerate discovery and improve manufacturability.

We value collaboration, data curation, and rigorous evaluation, with opportunities to contribute to publications and design iterations in a fast-paced, mission-driven environment.

Qualifications

• Ph.D. in computer science, computational biology, bioengineering, chemistry, physics, or related STEM field; or an M.S. with 2+ years of relevant experience; or a B.S. with 3+ years of relevant experience.
• Hands-on experience applying machine learning to sequence, structure, molecular, biological, or other scientific data.
• Proficiency in Python and a modern deep learning framework, with experience using GPU computing.
• Hands-on experience with active learning, Bayesian optimization, multi-objective optimization, quality-diversity methods, or related optimization approaches.
• Experience with generative models for proteins or molecules and exposure to physics-/structure-based scoring methods.

Responsabilités

• Build and refine generative design methods for antibody and VHH discovery.
• Translate AI advances into measurable impact on therapeutic discovery.
• Collaborate with diverse teams to accelerate design performance and discovery outcomes.
• Present findings to computational and experimental teams and contribute to publications.

Connaissances

Python

Deep learning

GPU computing

Communication skills

Multidisciplinary teamwork

Formation

Ph.D. in computer science, computational biology, bioengineering, chemistry, physics, or related STEM

M.S. with 2+ years of relevant experience

B.S. with 3+ years of relevant experience

Outils

PyTorch

TensorFlow

Bioinformatics tools

Rosetta

Structure data tools

Description du poste

Lilly’s Biotechnology Center in San Diego is expanding a generative design platform to create novel antibodies and biotherapeutics. You will join a cross-disciplinary team applying AI/ML, protein engineering, automation, and structural biology to accelerate discovery and improve manufacturability.

We value collaboration, data curation, and rigorous evaluation, with opportunities to contribute to publications and design iterations in a fast-paced, mission-driven environment.