Gene Editing Scientist for Reproductive Genetics

Preventive; South San Francisco (CA); Hybrid; USD 110,000 - 170,000; Full time

Job summary

Preventive is a public benefit corporation developing reproductive genetics technologies to prevent severe inherited diseases before birth. We seek a hands‑on experimentalist to build and optimize next‑generation gene editing systems for reproductive genetics, focusing on prime and base editing in cell‑based and embryo‑relevant assays.

Applicants should show a strong work ethic and high aptitude, with training as needed for specialized techniques.

Qualifications

• BS or higher in a relevant field (we care more about your experience than your formal education)
• 2+ years of industry experience in biotechnology.
• Demonstrated gene editing experience with next‑generation platforms (prime and/or base editing).
• Strong molecular biology skills.
• Proficiency in mammalian tissue culture, including sterile technique and basic cell‑based assays.
• Clear evidence of strong work ethic, high aptitude, and ownership in previous roles or projects.

Responsibilities

• Optimize prime and base editing systems in mammalian cells and embryo‑relevant models including protein and guide engineering.
• Execute molecular biology workflows, including cloning, PCR/qPCR, amplicon prep, and sequencing‑based analysis.
• Measure editing efficiency, byproducts, mosaicism, specificity, and off‑target activity.
• Support NGS and single‑cell workflows to characterize editing outcomes and embryo‑relevant biology.
• Translate cell‑based editing results into oocyte, zygote, and embryo experiments.
• Work across molecular biology, genomics, embryology, and in vivo teams to solve technical problems.

Skills

Gene editing experience

Mammalian cell culture

Molecular biology

Cloning

PCR/qPCR

Education

BS or higher in a relevant field

Tools

Next‑generation sequencing

Single-cell workflows

Job description

Preventive is a public benefit corporation developing reproductive genetics technologies to prevent severe inherited diseases before birth. We seek a hands‑on experimentalist to build and optimize next‑generation gene editing systems for reproductive genetics, focusing on prime and base editing in cell‑based and embryo‑relevant assays.

Applicants should show a strong work ethic and high aptitude, with training as needed for specialized techniques.