Flexible Antibody Formats - Valency Exploration - Intern

BioCT; Ridgefield (CT); Hybrid; USD 33.000 - 45.000; Vollzeit

Zusammenfassung

Boehringer Ingelheim is seeking an Intern to contribute to the development of an innovative antibody engineering platform. You will work on enabling rapid conversion between IgG1KO and ZM21 formats through hinge engineering and protease-mediated strategies.

You will gain hands-on experience in antibody engineering, molecular biology, protein expression, purification, and biophysical characterization while collaborating with a multidisciplinary team of scientists developing next-generation

Qualifikationen

• Graduate or advanced degree student in good academic standing.
• Enrolled at an accredited college or university for the duration of the internship.
• Overall GPA 3.0 on a 4.0 scale preferred.
• Major or minor in Biology, Biochemistry, Biotechnology, Chemical Engineering, Biomedical Engineering or related field.
• Undergraduate students: at least 12 credit hours.
• Graduate/advanced: at least 9 credit hours.
• Basic understanding of molecular biology, protein biochemistry, or antibody engineering.
• Strong analytical, organizational, and communication skills.
• Ability to work independently and collaboratively in a team.

Aufgaben

• Design and generate antibody variants using molecular biology techniques.
• Express recombinant antibodies using transient mammalian expression systems.
• Purify antibody molecules using standard protein purification methods.
• Characterize protein expression, yield, purity, and product quality attributes.
• Document findings and communicate results through presentations and written summaries.
• Collaborate with scientists across Biotherapeutics Discovery.

Kenntnisse

Analytical skills

Organizational skills

Communication skills

Team collaboration

Independent work

Ausbildung

Biology

Biochemistry

Biotechnology

Chemical Engineering

Biomedical Engineering

GPA 3.0 preferred

Jobbeschreibung

Description

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development, and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies' success. We realize that our strength and competitive advantage lie with our people. We support our employees in several ways to foster a healthy working environment, meaningful work, mobility, networking, and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.

Boehringer Ingelheim is currently seeking a talented and innovative Intern, you will contribute to the development of an innovative antibody engineering platform designed to accelerate multispecific antibody format evaluation. This project focuses on creating a flexible workflow that enables rapid conversion between IgG1KO and ZM21 antibody formats through hinge engineering and protease-mediated cleavage strategies.

The successful candidate will gain hands-on experience in antibody engineering, molecular biology, protein expression, purification, and biophysical characterization while working alongside a multidisciplinary team of scientists developing next-generation biotherapeutics.

Duties & Responsibilities

• Design and generate antibody variants using molecular biology techniques
• Express recombinant antibodies using transient mammalian expression systems
• Purify antibody molecules using standard protein purification methods
• Characterize protein expression, yield, purity, and product quality attributes
• Document findings and communicate results through presentations and written summaries
• Collaborate with scientists across Biotherapeutics Discovery

Requirements

• Must be a current graduate or advanced degree student in good academic standing.
• Student must be enrolled at an accredited college or university for the duration of the internship.
• Overall cumulative minimum GPA from last completed quarter/semester 3.0 GPA (on a 4.0 scale) preferred.
• Major or minor in Biology, Biochemistry, Biotechnology, Chemical Engineering, Biomedical Engineering or related field of internship.
• Undergraduate students must have completed at least 12 credit hours at current college or university.
• Graduate and advanced degree students must have completed at least 9 credit hours at current college or university.
• Basic understanding of molecular biology, protein biochemistry, or antibody engineering.
• Strong analytical, organizational, and communication skills.
• Ability to work independently and collaboratively in a team environment.

Desired Qualifications:

• Prior laboratory experience with molecular cloning, mutagenesis, mammalian cell culture, or protein purification.
• Familiarity with antibody structure and function.
• Experience analyzing biochemical or biophysical data.

Eligibility Requirements:

• Must be legally authorized to work in the United States without restriction.
• Must be willing to take a drug test and post-offer physical (if required).
• Must be 18 years of age or older.

Compensation Data

This position offers an hourly rate of $24.00 - $33.00 USD / hour commensurate with the level of degree program in which an applicant is actively enrolled. We continuously review market data and may adjust salary ranges as needed in the future. Benefits include medical coverage, paid time off, paid holidays, disability and life insurance benefits, and other company-sponsored benefits. For additional information regarding our benefits and Total Rewards offerings, please click here.