Biologics Engineering, Computational and Experimental Design of Multispecific Antibodies Intern

AstraZeneca; Gaithersburg (MD); On-site; USD 54,000 - 57,000; Full time

Job summary

AstraZeneca plc in Gaithersburg, MD is seeking rising seniors and Master’s level students for a 12-week internship in chemical/biological engineering or related fields. The role focuses on designing multispecific antibodies using computation and AI-enhanced methods, followed by production and characterization workflows.

Applicants should have experience in computational protein modeling/design and protein engineering, plus wet-lab skills in molecular cloning, purification, and in vitro and

Qualifications

• Design multispecific antibodies using computational design and AI-enhanced approaches.
• Experience in multispecific antibody production workflows.
• Characterize multispecific antibodies via functional and biophysical assays.
• Candidates must be rising seniors or Master’s students in Chemical Engineering, Biological Engineering or related field.
• US work authorization required; CPT not supported.
• Onsite reporting to Gaithersburg, MD 5 days/week; no relocation provided.
• Compensation: $39–$41.50 per hour.

Responsibilities

• Design multispecific antibodies using computational and AI-enhanced approaches.
• Produce multispecific antibodies using appropriate expression and purification workflows.
• Characterize multispecific antibodies through functional and biophysical assays.

Skills

Computational protein modeling/design

Protein engineering

Molecular cloning

Protein purification

In vitro and cell-based assays

Job description

We are looking for rising seniors and Master's level students studying Chemical Engineering, Biological Engineering or a related field for a 12-week internship role at our site in Gaithersburg, MD from May 24, 2027 to August 13, 2027.

Position Description

• Design multispecific antibodies using computational and AI-enhanced approaches.
• Produce multispecific antibodies using appropriate expression and purification workflows.
• Characterize multispecific antibodies through functional and biophysical assays.

Position Requirements

• Rising seniors and Master's level students studying Chemical Engineering, Biological Engineering or a related field.
• Required experience includes computational protein modeling/design and protein engineering.
• Required wet-lab skills include molecular cloning, protein purification, and in vitro and cell-based assays.
• Candidates must have an expected graduation date after August 2027.
• US Work Authorization is required at time of application.
• This role will not be granting CPT support.
• Ability to report onsite to Gaithersburg, MD site 5 days per week. This role will not provide relocation assistance.
• Compensation: $39 - $41.50 per hour.

#EarlyTalent

Date Posted: 11-Nov-2026

Closing Date: 01-Dec-2026

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