Fermentation Process Scientist II for Recombinant Peptides

BioSpace; Irvine (CA); Sur place; USD 110 000 - 150 000; Plein temps

Avantages offerts par ce poste

Medical/dental/vision insurance

401(k) plan

Paid time off

Résumé du poste

AbbVie’s Biologics CMC organization seeks a fermentation scientist to advance microbial processes for recombinant peptide production. You will design and execute fermentation studies, optimize hosts like E.

coli and yeast, and collaborate with cross-functional teams to generate reliable data for project goals. The role involves bench-scale bioreactors, data analysis, literature-informed problem solving, and ensuring adherence to GxP practices as applicable.

Qualifications

• Master’s degree or equivalent with 5+ years of relevant experience or Bachelor’s degree or equivalent with 7+ years of relevant experience, is required.
• Theoretical and practical knowledge of microbial cultivation and fermentation, preferably using E. coli and/or yeast.
• Demonstrated ability to independently design, execute, and interpret critical experiments to answer scientific questions.
• Demonstrated ability to develop, adapt, and optimize experimental methods and techniques in response to project needs.
• Experience operating bioreactors and applying fermentation parameters such as pH, temperature, agitation, aeration, and dissolved oxygen.

Responsabilités

• Independently design, execute, and interpret critical fermentation experiments to answer scientific questions and advance project goals.
• Develop and optimize microbial cultivation and fermentation processes, including work with hosts such as E. coli and yeast.
• Evaluate the effects of media composition, inoculum conditions, feed strategies, induction conditions, temperature, pH, agitation, aeration, and dissolved oxygen on growth and product expression.
• Operate, maintain, and optimize bench-scale bioreactors and support microscale, parallel, and scale-down fermentation studies.
• Collaborate with strain-development colleagues to screen and characterize microbial clones and expression systems.
• Analyze fermentation data—including growth, substrate use, process parameters, product titer, and yield—and place findings in the relevant scientific context.
• Troubleshoot experiments and instrumentation, adapting or developing methods to meet changing project needs.

Connaissances

Microbial fermentation

Bioreactor operation

Data interpretation

Scientific writing

Cross-functional collaboration

Formation

Master’s degree or equivalent in relevant field

Bachelor’s degree or equivalent in relevant field

Description du poste

AbbVie’s Biologics CMC organization seeks a fermentation scientist to advance microbial processes for recombinant peptide production. You will design and execute fermentation studies, optimize hosts like E.

coli and yeast, and collaborate with cross-functional teams to generate reliable data for project goals. The role involves bench-scale bioreactors, data analysis, literature-informed problem solving, and ensuring adherence to GxP practices as applicable.