Fermentation Pilot Plant Operator

Manus; Augusta (GA); On-site; USD 60,000 - 85,000; Full time

Benefits offered by this job

None

Job summary

Manus Bio in Augusta, GA is seeking a Pilot Plant Fermentation Operator to support manufacturing and process development. You will work with the process development team to run fermentation operations, collect data, and help optimize downstream purification steps.

The role requires a high school diploma, at least 3 years of downstream or related plant operator experience, and a collaborative mindset. You will operate equipment, maintain cleanroom standards, and contribute to safe, compliant

Qualifications

• High school diploma or GED required.
• Strong teamwork and collaboration skills.
• Willingness to work in startup environment.
• Basic PC skills including Windows & MS Office.
• Must follow safety and cleanroom practices.

Responsibilities

• Interface with process development team to provide resources to solve fermentation and product isolation challenges.
• Execute and help evaluate experiments.
• Perform downstream purification operations including centrifugation, chromatography (e.g., affinity, ion exchange), filtration (TFF, depth, sterile).
• Set up, operate, and clean process equipment such as columns, tanks, and filtration systems.
• Collect, label, and process in‑process and final product samples.
• Monitor process parameters, record data, and ensure batch documentation is completed accurately.
• Perform cleaning and sterilization of equipment and cleanroom areas (CIP/SIP procedures).
• Assist in deviation investigations and continuous improvement initiatives.
• Collaborate with upstream and quality departments to ensure efficient process flow and product quality.
• Maintain inventory of DSP consumables and request resupply as needed.
• Become familiar with all required batch records, execute according to the batch records and ensure clear communication of the targeted design parameters.
• Execute day‑to‑day Pilot Plant activities, coordinating equipment maintenance and installation activities, troubleshooting process upsets, troubleshooting equipment and instrumentation problems, optimizing operations, addressing contamination issues, addressing downtime or other runtime losses.
• Maintain the upkeep of the Pilot Plant equipment through the process of initiating work notifications/work orders and maintenance scheduling; be capable of correcting minor maintenance issues.
• Adhere to company environmental, safety, and health policies and procedure. Ensure Pilot Plant compliance with safety and environmental regulations.
• Physical demand requirements are more than sedentary work due to inspection of equipment. Must be able to climb stairs and ladders. Must be able to lift 50 pounds.
• Must be able to wear the required protective equipment, including respirators when needed.
• Work schedule is considered shift but will vary depending on manufacturing plan and other extraordinary conditions.

Skills

Team communication

Attention to detail

Problem solving

Team player

Flexibility

Education

High school diploma or GED

Tools

SAP

DeltaV controls

Microsoft Office

Job description

Manus Bio in Augusta, GA is seeking a Pilot Plant Fermentation Operator to support manufacturing and process development. You will work with the process development team to run fermentation operations, collect data, and help optimize downstream purification steps.

The role requires a high school diploma, at least 3 years of downstream or related plant operator experience, and a collaborative mindset. You will operate equipment, maintain cleanroom standards, and contribute to safe, compliant