Executive Director, Trade & Distribution

Initial Therapeutics, Inc.; Watertown (MA); On-site; USD 257,500 - 326,167; Full time

Job summary

EyePoint Pharmaceuticals seeks an Executive Director, Trade and Distribution to design, build, and lead the U.S. retinal portfolio distribution and channel strategy.

You will own all contracts, ensure compliant product flow from manufacturing to patient administration, and build the network from the ground up. The role requires strategic design and hands-on execution across trade operations, with strong leadership to scale post-launch and ensure availability for Medicare Part B buy-and-bill

Qualifications

• 12+ years in pharmaceutical/biotech trade, distribution, or channel management with senior ownership.
• Experience building or launching a specialty distribution model for Medicare Part B buy-and-bill products.
• Retina/ophthalmology or specialty injectable product experience preferred.

Responsibilities

• Design end-to-end U.S. distribution model and select SD/SP networks.
• Negotiate and manage distribution contracts, terms of sale, revenue recognition, and payment terms.
• Lead launch readiness: order-to-cash, inventory positioning, dating, and shelf-life management.

Skills

Trade & Distribution leadership

Specialty distribution design

Contract negotiation

Ophthalmology/retina domain

3PL/logistics management

DSCSA/serialization knowledge

First-launch build experience

Education

Bachelor's degree

MBA or healthcare MBA

Tools

EDI data (852/867/844)

Trade contracts management systems

Job description

The Commercial team at EyePoint focuses on bringing innovative therapies to patients by ensuring healthcare providers, partners, and communities have access to treatment, reimbursement, and are able to use the product appropriately. This team uses data-driven insights, market access strategies, and a patient-centric approach to improve awareness, access, and adoption of EyePoint’s therapies to help improve vision outcomes for people with serious retinal diseases.

EyePoint Pharmaceuticals is seeking an Executive Director, Trade and Distribution to design, build, and lead the commercial distribution and channel strategy supporting the launch of the Company's retina portfolio. This leader will architect the specialty distribution and specialty pharmacy network, own all channel partner contracting and operations, and ensure reliable, compliant, and financially sound product flow from manufacturing through to the point of patient administration for a Medicare Part B buy-and-bill therapy. This is a build-from-the-ground-up role requiring both strategic channel design and hands-on operational and contract execution.

Key Accountabilities

Distribution Strategy & Channel Architecture

• Design and own the end-to-end U.S. distribution model for the retina portfolio - evaluating open, limited, and exclusive specialty distribution architectures and recommending the model that best supports rapid, compliant product availability at launch
• Build the Specialty Distributor (SD) and Specialty Pharmacy (SP) network from the ground up, including partner selection, onboarding, and integration with 3PL warehousing and logistics
• Partner with BD, Marketing, and Market Access leadership to align distribution strategy with the overall launch and commercial plan

Channel Partner & Contract Management

• Negotiate and manage all distribution contracts and commercial terms with wholesalers, specialty distributors, specialty pharmacies, and 3PLs - including terms of sale, fees-for-service, revenue recognition, and payment/collections
• Own trade policies and procedures: ordering, returns, replacements, credit/rebill requests, inventory management, and chargeback processing - executing against contract prices and government pricing terms set by National Payer Accounts
• Serve as the primary point of contact for channel partners, resolving field/provider-reported service and access issues in coordination with National Accounts and Sales

Launch Execution & Operations

• Lead trade readiness for launch: order-to-cash setup, inventory positioning at 3PLs/SDs, product dating and shelf-life management in partnership with Supply Chain
• Own distribution and channel data flows (e.g., 852/867/844 EDI feeds, chargeback data, specialty pharmacy dispense/inventory data) and ensure data quality in partnership with IT and Commercial Analytics
• Provide channel-side inputs (chargebacks, distribution fees, inventory carry costs) into the gross-to-net and P&L model that Finance consolidates alongside National Payer Accounts' payer-mix assumptions

Compliance & Quality

• Ensure full compliance with DSCSA/serialization, pedigree, and drug distribution accreditation standards (e.g., HDA) across all channel partners
• Oversee channel partner facility audits, recall effectiveness checks, and adherence to national regulatory and licensing requirements
• Liaise with Legal and Compliance to ensure all trade contracts and programs meet applicable laws and regulations

Cross-Functional & Executive Engagement

• Represent trade and distribution strategy and performance to the CCO, executive team, and Board as needed
• Partner with the VP, Head of National Payer Accounts and VP Patient Services to ensure SD/SP capacity and product availability are launch-ready to support the HUB-led patient onboarding journey
• Build and lead the Trade & Distribution function/team as it scales post-launch, operating in a “player-coach” capacity during early-stage build-out

Qualifications

Required

• 12+ years in pharmaceutical/biotech trade, distribution, or channel management, including experience at the Director/Senior Director level or above with direct contract negotiation ownership
• Direct experience building or launching a specialty distribution model for a Medicare Part B buy-and-bill product
• Retina, ophthalmology, or broader specialty injectable/infused product experience strongly preferred
• Deep working knowledge of specialty distributor and specialty pharmacy contracting, wholesaler relationships, and 3PL/logistics management
• Hands-on knowledge of trade operations mechanics: chargeback processing, EDI data (852/867/844), returns/credit-rebill, and inventory management
• Working knowledge of DSCSA/serialization requirements and drug distribution accreditation standards (e.g., HDA)
• Demonstrated success building a trade and distribution function from scratch at a small/mid-cap biotech ahead of a first launch
• Bachelor's degree required; advanced degree (MBA, healthcare-related) a plus

Preferred

• Existing relationships across major specialty distributors, specialty pharmacies, and 3PL providers relevant to retina/buy-and-bill products
• Familiarity with the evolving MFN/Part B pricing policy landscape and its implications for channel economics

EyePoint is committed to fair andequitablecompensation practices.The salaryoffer iscommensuratewithEyePoint’scompensation philosophy and considers factors including but notlimited to education, training, experience, market conditions, criticality of the role and internal equity.

The target salary range for this position is listed below:

Salary Range

$257,500 - $326,167 USD

Envision Your Future

With the exciting energy of a winning culture and an exhilarating pace, we are an ophthalmology company committed topreventing blindnessby developing and commercializing innovative therapeutics.

The collective power of our values influences everything we do, and everything we do for you.

Transformational Innovation

We exist to change our patients’ lives through the power of sight. We are forward looking, embrace challenges with curiosity, and continuously seek to improve our products and ourselves by learning, problem-solving and pushing the limits of science and technology.

Unwavering Integrity

We recognize our responsibility to our patients, employees, and our community, and value the trust they put in us. We set a high ethical bar and expect responsible leadership at every level to ensure we serve those who matter most to us.

Compassionate Excellence

We believe that fun and excellence can coexist. We foster a culture where enjoying the work we do and caring for each other are as important as delivering exceptional outcomes.

Inclusive Collaboration

We strive to see through the eyes of others and work as one team. We appreciate one another’s differences and perspectives, and ensure everyone feels valued, respected and encouraged to bring their ideas forward.

EyePointis proud to be an equal opportunity employer. We believe that diversity and inclusion among our colleagues is critical to our success as a company, and we seek to recruit, develop, and retain the most talented people from a diverse candidate pool. All applicants will be considered for employment without attention to age, race, color, religion, sex, sexual orientation, gender identity, national origin, veteran, or disability status.