Executive Director, Operations Lead

Scorpion Therapeutics; Waltham (MA); On-site; USD 180,000 - 230,000; Full time

Job summary

Madrigal is seeking an Executive Director, Operations Lead to oversee clinical trial management for the MASH program, including Rezdiffra. The role requires driving trial strategy end-to-end, managing CROs, budgets, and cross-functional collaboration to ensure regulatory readiness and successful trial execution.

The ideal candidate has 10+ years in clinical operations across multiple trial phases, with experience in metabolic or liver-related therapeutics and a strong track record in global drug

Qualifications

• Bachelor’s in Life Sciences, Nursing, or Pharmacy.
• MS or PharmD preferred.
• minimum 10 years in clinical operations with experience in early to late-stage trials.

Responsibilities

• Develop and execute clinical trial strategies from planning to close-out.
• Manage CRO relationships.
• Oversee budgets and site interactions.
• Ensure compliance with industry standards (ICH-GCP, SOPs).
• Lead team development.
• Support regulatory submissions.

Skills

Clinical operations

Education

Bachelor’s degree in Life Sciences/Nursing/Pharmacy

MS or PharmD

Job description

Role

Executive Director, Operations Lead overseeing clinical trial management for Madrigal's MASH therapeutics, including Rezdiffra.

Responsibilities

• develop and execute clinical trial strategies from planning to close-out
• manage CRO relationships
• oversee budgets and site interactions
• ensure compliance with industry standards (ICH-GCP, SOPs)
• lead team development
• support regulatory submissions

Requirements

• Bachelor's in Life Sciences, Nursing, or Pharmacy
• MS or PharmD preferred
• minimum 10 years in clinical operations with experience in early to late-stage trials, ideally in metabolic or liver-related therapeutics

High-Value

• expertise in global drug development
• multi-national pivotal trials
• regulatory interactions (FDA, EMA)
• protocol/ISR development

Collaboration

cross-functional engagement with Biometrics, Regulatory, and Quality teams.

Work Setup

not specified.