Enterprise Applications Development Lead

Praxis Precision Medicines, Inc.; United States; Remote; USD 130,000 - 150,000; Full time

Benefits offered by this job

Life insurance

AD&D

Disability benefits

401(k) matching

Stock incentives

ESPP

Quarterly bonus

Wellness benefit

Generous PTO

Paid holidays

Shutdowns

Job summary

Praxis Precision Medicines, Inc. is seeking an Enterprise Applications Development Lead to build, integrate, and support systems that enable our teams to operate reliably as we scale for commercial launch. This remote role focuses on hands-on work: configuring SaaS applications, developing SQL, and automating workflows.

You’ll own delivery and reliability for assigned applications, collaborating with Commercial, Finance, People, and IT. Leadership comes from technical excellence and execution.

Qualifications

• 8+ years of experience in enterprise applications, ERP/CRM, or data engineering with hands-on delivery and production support.
• Strong SQL development, data modeling, troubleshooting, data quality, and performance tuning; Python scripting experience.
• Experience configuring or supporting enterprise SaaS platforms and ERP/CRM integrations (e.g., SAP, Salesforce, Dynamics).
• Hands-on ETL/ELT development and integrations using APIs, middleware, or file exchanges with reliability focus.
• Ability to translate business needs into technical designs and drive deployment and ongoing support.
• Experience with Git, issue tracking, documentation, and disciplined release practices.

Responsibilities

• Build, configure, administer, and support enterprise apps and workflows across SaaS, including SAP, Salesforce/Veeva, Greenhouse, and Ketch.
• Develop and maintain SQL queries, data models, integrations, and automated workflows with robust error handling and monitoring.
• Support SAP and CRM implementations through data mapping, migration, integration development, testing, and troubleshooting with business owners.
• Connect application data to commercial reporting with Data & Analytics; maintain tested queries and access procedures.
• Translate needs into clear requirements and designs; configure standard capabilities or develop custom solutions.
• Own issues through resolution, runbooks, vendor coordination, and cross-training for backup coverage.
• Coordinate work with vendors and internal teams; maintain docs, contacts, and license usage; flag risks to IT leadership.
• Use version control, testing, and compliant release practices; work with Security and IT Validation on access controls and validation evidence.

Skills

SQL development

SaaS configuration

ETL/ELT development

Python scripting

ERP/CRM integration

Data modeling

Git/version control

Stakeholder communication

Tools

SAP

Salesforce

Veeva

Greenhouse

Ketch

Job description

Location: This position may be performed remotely, but requires the flexibility and willingness to travel as needed.

The Opportunity

Praxis is scaling for commercial launch. We’re looking for an Enterprise Applications Development Lead to build, integrate, and support the systems that help our teams operate reliably as we grow.

You will spend the majority of your time on hands‑on work: configuring SaaS applications, developing SQL and data integrations, automating workflows, investigating issues, and delivering tested improvements. Initial priorities include enterprise application support, ERP and CRM integrations, and dependable access to commercial data.

You will own technical delivery and day‑to‑day reliability for assigned applications, working with Commercial, Finance, the People Team, and IT. This is an individual contributor role with leadership through technical expertise and execution. You will work within the priorities and architecture established with IT leadership, partnering with application engineering, data engineering, security, and validation colleagues.

Primary Responsibilities

• Build, configure, administer, and support assigned enterprise applications and workflows across the SaaS environment, including systems such as SAP, Salesforce/Veeva, Greenhouse, and Ketch.
• Develop and maintain SQL queries, data models, integrations, and automated workflows using APIs, middleware, file exchanges, and scripting. Implement reconciliation, error handling, monitoring, and recovery procedures.
• Support SAP and CRM implementations and enhancements through data mapping, migration, integration development, testing, and production troubleshooting with business owners and implementation partners.
• Partner with Data & Analytics to connect application data to commercial reporting and the commercial data foundation. Maintain tested SQL queries and documented access procedures so critical monitoring can continue when AI interfaces are unavailable.
• Translate business needs into clear requirements, practical technical designs, and deliverable work items. Configure standard platform capabilities where appropriate and develop custom solutions when justified.
• Own issues through resolution: diagnose failures, coordinate vendor support, communicate business impact, and address recurring causes. Maintain runbooks and cross‑train colleagues to provide dependable backup coverage.
• Coordinate technical work with vendors and internal teams. Maintain application documentation, support contacts, and license usage information; recommend simplification and flag renewal or support risks to IT leadership.
• Use version control, peer review, repeatable deployment, and appropriate testing. Partner with Security and IT Validation on access controls, change documentation, and validation evidence for regulated workflows.

Qualifications

• 8+ years of relevant experience in enterprise applications, ERP/CRM systems, database development, or data engineering, with recent hands‑on delivery and production support responsibilities.
• Strong SQL development skills, including relational data modeling, troubleshooting, data quality, and performance tuning; practical scripting experience with Python or a comparable language.
• Experience configuring or supporting enterprise SaaS platforms and integrating ERP or CRM systems. Relevant experience may include Microsoft Dynamics 365, SAP, Salesforce, or comparable platforms.
• Hands‑on experience building and maintaining ETL/ELT processes and integrations using APIs, middleware, or file‑based exchanges, with attention to reliability and recoverability.
• Ability to work directly with business users, clarify requirements, test solutions, and carry changes through deployment and ongoing support.
• Experience with Git or comparable version control, issue tracking, technical documentation, and disciplined release practices.
• The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement. You'll need comfort with screen work, basic hand coordination, and focus. Reasonable accommodations may be made to enable individuals with disabilities to perform these functions.

Annualized Base Salary $130,000 — $150,000 USD

Compensation & Benefits

At Praxis, we believe that taking care of our people (and their people) is important, so we provide a world class benefits package to help you thrive. This includes 99% of the premium paid for medical, dental and vision plans.

• Company‑paid life insurance
• AD&D
• Disability benefits
• Voluntary plans to personalize coverage
• Matching dollar‑for‑dollar up to 6% on eligible 401(k) contributions
• Long‑term stock incentives and ESPP
• Discretionary quarterly bonus
• Extremely flexible wellness benefit
• Generous PTO
• Paid holidays
• Company‑wide shutdowns

Not to mention, you'll also be joining a phenomenal crew of colleagues who are smart, engaged and inspiring. We aim high, collaborate hard, and produce results. Let’s achieve the impossible together!

Company Overview

Praxis Precision Medicines is a clinical‑stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders. Our core Values of Trust , Ownership , Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.

Diversity, Equity & Inclusion

Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE ® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.

Praxis does not accept unsolicited submissions from recruitment agencies for open positions. We ask all recruitment agencies to refrain from contacting any Praxis employee regarding any position. All unsolicited resumes submitted by recruitment agencies to any Praxis employee in any form or method will be deemed to be the property of Praxis, and Praxis explicitly reserves the right to hire those candidate(s) without any financial obligation to the recruitment agency.