Engineer

System One; Boston (MA); On-site; USD 80,000 - 94,000; Full time

Job summary

System One, Inc. in Boston, MA seeks an Engineer (Contract) to support design, manufacturing and characterization of lipid nanoparticles (LNPs) for CPPs and CMAs affecting CQAs.

The role is onsite in Boston with standard hours and a 9am–5pm schedule, Monday through Friday. Responsibilities include running DoEs, defining equipment specs, drafting procedures, writing protocols, analyzing data, and presenting findings.

Qualifications

• 2+ years of relevant industry experience.
• Experience with lipid nanoparticle formulations and analytical methods preferred.
• Knowledge of GMP environments and lab best practices.

Responsibilities

• Support design and execution of experiments incl. DoEs for LNP tech and CPPs/CMA.
• Define equipment specs, draft procedures, and set operating parameters.
• Write protocols, run experiments, analyze data, and present results.
• Order supplies and maintain safe lab operations.
• Multi-task across projects and collaborate with cross-functional teams.

Skills

LNP formulations

Analytical characterization

GMP familiarity

Education

B.S./M.S. in chemical engineering or related field

Tools

TFF

Sterile filtration

Job description

Job Title: Engineer

Location: Boston, MA

Type: Contract

Compensation: $58.00-$68.25/hr

Work Model: Onsite

Hours: 9am to 5pm MF

Overview

Support the design, manufacturing and characterization of lipid nanoparticles (LNPs) for screening critical process parameters (CPPs) and critical material attributes (CMAs) that impact critical quality attributes (CQAs).

Responsibilities

• Support the design and execution of a wide range of experiments including DoEs to advance LNP technology and process development.
• Participate in defining equipment specification/selection, draft procedures and recommended operating parameters/ranges
• Write protocols, perform experiments, organize and analyze data, interpret results, record experiments in an electronic lab notebook, and summarize work in presentations and technical reports
• Assist in ordering supplies, making reagents, and maintaining a safe and high-performing laboratory
• Multi-task across several projects and manage time effectively to achieve results Collaborate with multiple cross-functional teams and execute other duties as assigned

Requirements

• Bachelor’s/Master’s degree in chemical engineering, bioengineering, chemistry, pharmaceutical sciences, or another related field with 2+ years of relevant industry experience.
• Experience with lipid nanoparticle formulations and analytical characterization methods (Preferred)
• Strong problem-solving skills, and creative/innovative approach in problem solving.
• Ability to work independently and in very dynamic interdisciplinary team environments. Proven record in working with partners/collaborators is desirable.
• Organized, detail-oriented, and innovative self-starter who continuously seeks to improve existing laboratory methods and processes.
• Effective verbal and written communication skills; proficiency in literature search and relevant computer software skills are required.
• Knowledge of practices and equipment used to run manufacturing processes in a GMP environment, including TFF, sterile filtration, single-use technology, and sterile/aseptic processing preferred.

System One, and its subsidiaries including Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.
System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.