Downstream Research Associates – Process Development

BioTalent; Tustin (CA); On-site; USD 70,000 - 110,000; Full time

Benefits offered by this job

Hourly pay

Bonus

Equity

Comprehensive benefits

Job summary

BioTalent is seeking a Research Associate or Lead Research Associate (Downstream) to contribute to the development and optimization of downstream purification processes for monoclonal antibodies and recombinant proteins. The role involves operating purification chromatography and analytical techniques in a regulated setting.

Ideal candidates will have downstream process development experience, experience with biologics or CDMOs, and the ability to design experiments, analyze data, and report

Qualifications

• Downstream purification experience with chromatography and filtration.
• Biopharmaceutical or CDMO experience preferred.
• Strong experimental design, data analysis and technical reporting skills.

Responsibilities

• Develop and optimize downstream processes.
• Lead purification studies and troubleshoot challenges.
• Support scale-up and technology transfer to manufacturing.
• Collaborate with cross‑functional teams on projects.

Skills

Downstream process development

Monoclonal antibodies

Recombinant proteins

Education

Bachelor's degree in life sciences

Tools

ÄKTA/FPLC systems

HPLC

SDS-PAGE

Job description

Research Associate & Lead Research Associate - Process Development (Downstream)

Join a team developing the next generation of biologic therapies! We're looking for talented scientists with downstream purification experience to support the development and optimization of processes for monoclonal antibodies, recombinant proteins, and other biologics.

We're hiring for two levels:

1-2 years of biopharmaceutical industry experience

Perfect for early-career professionals looking to grow their expertise in downstream process development.

3-4 years of biopharmaceutical industry experience

We're looking for a technical leader who can drive downstream process development, lead purification studies, troubleshoot complex challenges, support process scale-up and technology transfer, and serve as a subject matter expert within cross-functional teams.

What you'll be working on:

• Downstream process development and optimization
• Protein purification using chromatography and filtration
• Operating ÄKTA/FPLC systems
• HPLC, SDS-PAGE, A280, and other analytical techniques
• Experimental design, data analysis, and technical reporting
• Supporting scale-up and technology transfer to manufacturing

Ideal background:

• Downstream Process Development
• Monoclonal Antibodies or Recombinant Proteins
• Biopharmaceutical or CDMO experience

• Hourly pay, bonus, equity, and comprehensive benefits.
• Work on impactful products in a regulated, high-quality environment
• Collaborate with cross-functional global teams
• Grow your career in a dynamic and innovative organization

Work Authorization:

Applicants must be authorized to work for any employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time