Downstream Process Scientist - Viral Vector Manufacturing

Eurofins PSS Insourcing Solutions; Spring House (PA); On-site; USD 65,000 - 90,000; Full time

Benefits offered by this job

Medical insurance

Dental insurance

Vision insurance

Life insurance

Disability insurance

401(k) with company match

Paid vacation and holidays

Job summary

Eurofins USA PSS Insourcing Solutions is seeking an experienced scientist to support downstream process development for viral vectors manufacturing. You will execute TFF, support Clarification, Nuclease Treatment, Filtration, and AEX chromatography, and help with column packing.

You will document parameters, manage project materials, and communicate findings to the team. A life sciences degree with 2+ years downstream experience or a related Master’s with 0-2 years is required, with GMP

Qualifications

• Bachelor's degree in life sciences with 2+ years downstream experience; Master's with 0–2 years acceptable.
• Hands-on experience in purification of proteins or biologics.
• Broad knowledge in chromatography techniques and purification process development.
• Ability to document work accurately in notebooks, protocols, reports and electronic systems.

Responsibilities

• Execute Tangential Flow Filtration (TFF) operations, including setup, processing, monitoring, and documentation.
• Support downstream processing activities: Clarification, Nuclease Treatment, Filtration and AKTA-based chromatography.
• Perform and support column packing activities.
• Capture, maintain, and document process parameters and analytical data in the Master Data File.
• Assist with inventory management and procurement of project supplies.
• Record and analyze experimental data, verify data integrity and accuracy.
• Report and summarize findings to the project team.
• Write technical documents and main work records in electronic notebooks.

Skills

Downstream processing

Protein purification

Chromatography

Data documentation

Education

Bachelor's degree in life sciences

Master's degree in life sciences

Tools

AKTA chromatography

Tangential Flow Filtration (TFF)

Job description

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.

The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. It also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in‑vitro diagnostic products.

In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.

In 2021, Eurofins generated total revenues of EUR 6.72 billion, and has been among the best performing stocks in Europe over the past 20 years.

Job Description

This role is expected to perform experiments to support downstream process development activities for viral vectors manufacturing.

• Execute Tangential Flow Filtration (TFF) operations, including system setup, processing, monitoring, and documentation
• Support downstream processing activities, including Clarification, Nuclease Treatment, Fitler Screening, Sterile Filtration and AEX chromatography (both manual and AKTA-based operations)
• Perform and support column packing activities
• Capture, maintain, and document process parameters and analytical data within the project Master Data File
• Assist with inventory management and the procurement of project supplies to ensure material availability and operational continuity
• Record and analyze experimental data, verify data integrity and accuracy
• Report/summarize findings to the project team
• Write technical documents and main work records in electronic notebooks

Qualifications

Minimum Qualifications

• Bachelor’s degree in life sciences or a related scientific discipline is required with 2+ years of direct Downstream experience, Masters degree with 0-2 years experience
• Hands‑on experience in purification of proteins or biologics is required
• Broad knowledge in chromatography techniques and purification process development is required
• Ability to document work accurately in notebooks, protocols, reports, and electronic systems

Other Qualifications

• Strong scientific, organisational, communication, and attention‑to‑detail skills
• Authorization to work in the United States indefinitely without restriction or sponsorship

Preferred Experience

• GMP knowledge and experience working in a regulated laboratory environment.
• Previous experience with transfer of a purification process to clinical and commercial GMP manufacturing is preferred

Additional Information

This position is Full-Time, Monday - Friday, 8:00 a.m. - 5:00 p.m.

• Excellent full‑time benefits including comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays

Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.