Downstream Process Development Scientist – Onsite

Catalent Pharma Solutions; Madison (WI); On-site; USD 110,000 - 150,000; Full time

Benefits offered by this job

Day-one medical, dental, and vision

401(k) with company match

Tuition reimbursement

Generous paid time off and holidays

Professional development opportunities

Job summary

Catalent Madison is seeking Scientists, Process Development – Downstream to advance purification process development for biologics. You will independently perform downstream purification experiments, optimize processes for mAbs and bispecific constructs, and serve as technical lead on client development and transfer projects.

You will author GMP‑compliant documents, analyze complex data, and mentor junior staff, collaborating across functions in a fast-paced, onsite environment at the Madison

Qualifications

• Bachelor’s degree in STEM with 6+ years relevant experience or Master’s with 3+ years; PhD with relevant academic experience.
• Hands-on experience with process-scale chromatography and filtration (chromatography, tangential flow filtration, normal flow filtration).
• Experience operating ÄKTA platforms and chromatography workstations.
• Knowledge of protein purification principles, scale-up concepts, and chromatography modes.
• Strong GDP, aseptic techniques, and technical document authoring (protocols, SOPs, batch records).
• Ability to design, execute, analyze, and troubleshoot complex lab experiments under accelerated timelines.
• Proficiency with Microsoft Office and lab software systems.

Responsibilities

• Independently perform downstream purification experiments, including automated chromatography, filtration, and TFF/DF.
• Lead the design, optimization, and characterization of downstream purification operations for mAbs and bispecific constructs.
• Serve as technical lead for client development or transfer projects and communicate results clearly.
• Author, review, and maintain GMP‑compliant documents and batch production records.
• Mentor junior team members and analyze complex data to drive process improvements.

Skills

Lab purification

Chromatography

TFF/UF/DF

GDP & GMP

Data analysis

Technical writing

Mentorship

Cross-functional

Education

Bachelor's degree in STEM

Master's degree

PhD

Tools

ÄKTA platforms

Job description

Catalent Madison is seeking Scientists, Process Development – Downstream to advance purification process development for biologics. You will independently perform downstream purification experiments, optimize processes for mAbs and bispecific constructs, and serve as technical lead on client development and transfer projects.

You will author GMP‑compliant documents, analyze complex data, and mentor junior staff, collaborating across functions in a fast-paced, onsite environment at the Madison