Downstream Process Associate — AAV Development

Zenith LifeScience LLC.; South San Francisco (CA); On-site; USD 55,000 - 85,000; Full time

Job summary

Zenith LifeScience LLC. in South San Francisco, CA, seeks an Associate I to participate in downstream areas of AAV development and production within process development for gene therapy programs and processes.

You will perform operations, support downstream purification unit operations, operate production equipment, document activities, and contribute to process improvements in a lab and office-based setting onsite.

Qualifications

• BS in Life Science or Engineering or equivalent experience.
• 0-2+ years in a pharmaceutical/biologics lab or manufacturing environment.
• Understanding of downstream process theory and equipment operation.
• Strong communication and teamwork abilities.
• Detail-oriented with record-keeping and documentation skills.
• Willingness to work outside normal business hours or overtime as required.

Responsibilities

• Perform all operations as directed per internal policies and other requirements.
• Execute experiments for downstream process development activities.
• Support downstream purification unit operations (such as chromatography, clarification, tangential flow filtration, sterile filtration, column packing, etc.).
• Operate production equipment, including inspection, setup, processing, and cleaning.
• Establish operating equipment specifications and improve operational techniques.
• Execute corrective measures addressing any issues in a timely manner.
• Attend safety meetings and follow all safety procedures, including maintaining a safe work environment.
• Ability to contribute to process improvement plans and drive to completion.
• Conduct operations in a collaborative, team environment with a positive attitude.
• Assist with process development experiments following defined experimental plans for non-GMP supply.
• Document preparation and maintenance for process development and research grade AAV production operations.
• Maintain digital records of all research production activities using in-house systems and shared digital document repositories.
• Follow laboratory safety procedures.
• Other duties as assigned.
• onsite work required (lab and office-centric position).

Skills

Effective communication

Record keeping

Problem solving

Independent work

Team collaboration

Education

BS in Life Science or Engineering

Tools

TFF systems

Chromatography

Sterile filtration

Job description

Zenith LifeScience LLC. in South San Francisco, CA, seeks an Associate I to participate in downstream areas of AAV development and production within process development for gene therapy programs and processes.

You will perform operations, support downstream purification unit operations, operate production equipment, document activities, and contribute to process improvements in a lab and office-based setting onsite.