Downstream Bioprocess Scientist — Pilot-Scale Purification

Zohorecruit; San Mateo (CA); On-site; USD 74,000 - 83,000; Full time

Job summary

Zohorecruit is seeking an Associate Scientist - Downstream Bioprocess in Foster City, CA, for a long-term contract. The role involves hands-on downstream purification, operating AKTA systems and UNICORN software, and supporting process scale-up and tech transfer.

The candidate will plan pilot-scale runs, prepare buffers, document activities, and ensure quality and safety in a fast-paced, schedule-driven environment. Weekend coverage may be required based on process needs.

Qualifications

• AA/AS degree with 4+ years of relevant industry experience in downstream purification or bioprocessing.
• BS/BE degree in Chemical Engineering, Biochemical Engineering, Biochemistry, Biology, or related field with 2+ years of relevant industry experience.
• Hands-on pilot-scale downstream bioprocessing experience is required.

Responsibilities

• Plan and execute pilot-scale downstream purification runs, including clarification, chromatography, TFF, viral filtration, depth filtration, and centrifugation.
• Prepare buffers and reagents and perform equipment setup, operation, cleaning, and teardown.
• Operate ÄKTA chromatography systems and UNICORN software for process execution and data collection.
• Pack and unpack chromatography columns and support chromatography process activities.
• Operate single-use equipment and filtration systems in a pilot-scale environment.
• Monitor process performance, analyze run data, identify process issues, and troubleshoot deviations in real time.
• Accurately document activities in SOPs, batch records, run sheets, and technical summaries.
• Communicate observations, process results, and troubleshooting findings to cross-functional teams.
• Support process scale-up, comparability studies, technology transfer, and laboratory readiness.
• Follow applicable safety, quality, and controlled-documentation procedures.
• Support occasional weekend or extended-hour coverage based on process schedules.

Skills

Downstream purification

Pilot-scale

AKTA systems

UNICORN

Data documentation

Education

AA/AS degree

BS/BE degree

Tools

ÄKTA systems

UNICORN

Job description

Zohorecruit is seeking an Associate Scientist - Downstream Bioprocess in Foster City, CA, for a long-term contract. The role involves hands-on downstream purification, operating AKTA systems and UNICORN software, and supporting process scale-up and tech transfer.

The candidate will plan pilot-scale runs, prepare buffers, document activities, and ensure quality and safety in a fast-paced, schedule-driven environment. Weekend coverage may be required based on process needs.