Director, US Commercial REMS Lead

Agios Pharmaceuticals Inc.; United States; Hybrid; USD 184,000 - 230,000; Full time

Benefits offered by this job

Premium benefits package

Competitive compensation

Remote or hybrid work options

Travel for events

Job summary

Agios Pharmaceuticals Inc. in the United States seeks a Director, US Commercial REMS Lead to drive REMS strategy across sales, field marketing, and patient support.

You will partner with Safety, Regulatory, and external vendors to translate REMS requirements into clear strategies and measurable outcomes. This leadership role requires 10+ years in biotech, strong cross-functional collaboration, and exceptional communication.

Qualifications

• Bachelor's degree in a scientific or business discipline.
• 10+ years in biotechnology or related industry.
• REMS experience within a Commercial environment.
• Strong cross-functional leadership and communication skills.
• Experience leading large, complex initiatives.

Responsibilities

• Serve as the primary Commercial liaison on REMS topics across internal stakeholders and external partners.
• Lead US Commercial strategy, operations, and insight generation across products with a REMS.
• Partner with Sales, Marketing, Training, Patient Services, Safety, QA and Regulatory teams to align strategy and execution.
• Lead the Commercial implementation of new REMS programs and ongoing compliance activities.
• Participate in cross-functional workstreams to improve REMS effectiveness.
• Support development of REMS training and materials for effective understanding and pull-through.
• Use data sources to generate Commercial insights and strengthen performance.
• Design, track, and present key REMS metrics to leadership.
• Foster collaboration across internal teams and external partners.

Skills

REMS experience

Cross-functional leadership

Operational excellence

Communication skills

People management

Strategic thinking

Education

Bachelor's degree

MBA or advanced degree

Job description

Director, US Commercial Risk Evaluation and Mitigation Strategies (REMS) Lead

Who we are:

At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative culture – one that sparks bold thinking and strengthens our connections with each other and with the rare disease communities we serve. We embrace diverse backgrounds with respect, active listening, and a commitment to inclusion – because our differences shape how we hire, collaborate, and innovate. Our team’s proven track record of executional excellence, combined with our depth of expertise and dedication, enables us to develop innovative medicines that reflect the priorities of rare disease communities. Our commitment is more than scientific – it’s deeply personal, grounded in the meaningful connections we have built.To learn more, visit www.agios.com and follow Agios on LinkedIn and X.

The impact you will make:

The Director, US Commercial REMS Lead drives US Commercial strategies, activities, and insight gathering related to REMS (Risk Evaluation and Mitigation Strategies). The Director leads the development, implementation, and ongoing management of commercial related REMS activities to support compliance, patient safety, and effective execution across sales, field marketing, patient support, specialty distribution and other customer-facing teams. This role requires partnership with Commercial, Safety, Regulatory, Patient Services, and external vendors to translate REMS requirements into clear strategies, aligned tactics, and measurable outcomes.

What you will do:

• Serve as the primary Commercial liaison on REMS topics across internal stakeholders and external partners. Attend select Governance and REMS core team meetings.
• Lead US Commercial strategy, operations, and insight generation across Agios products/indications with a REMS.
• Partner with Sales, Marketing, Commercial Training, Patient Services, Safety, Quality Assurance and Regulatory teams to align strategy, communications, and execution.
• Lead the Commercial implementation of new REMS programs/modifications and ongoing compliance activities.
• Participate in cross-functional workstreams to implement initiatives that improve REMS effectiveness and ensure ongoing success of the program.
• Support the development of Commercial REMS training, communication, and materials that enable effective REMS understanding and pull-through.
• Use multiple data sources to generate Commercial insights, refine strategy, and strengthen operational performance.
• Partner with Commercial Operations and Analytics to design, track, and present key commercial REMS related metrics and KPIs to leadership.
• Foster strong collaboration and accountability across internal teams and external partners.

What you bring:

• Bachelor’s degree in a scientific or business discipline.
• 10+ years of experience in biotechnology or a related industry.
• Demonstrated REMS experience within a Commercial environment.
• Strong record of high performance in operational and cross-functional roles.
• Experience leading large, complex, cross‑functional initiatives.
• Excellent communication skills and the ability to build strong partnerships.
• Strong understanding of compliance requirements and guidance governing REMS programs.
• High learning agility, sound judgment, and strong people skills.
• Experience leading people, projects, or both.
• MBA or other advanced degree preferred.
• Experience in rare disease preferred.

Work Location:

Location Agnostic: Work location for this role is based on employee's individual preference. This role has the ability to be either remote in the US or hybrid in our Cambridge Headquarters. Hybrid schedules vary but are generally less than 3 days per week onsite and hybrid employees are expected to live within commutable distance to our Cambridge Headquarters. Remote employees work entirely from home except for attending Company sponsored events/ meetings. For employees who choose to work remotely, travel may be required for certain company events commensurate to the above job description.

What we will give you:

• Deliberate Development. Your professional growth as one of our top priorities.
• We’re all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you’re at your best, we’re at our best.
• Premium benefits package. We invest in the health, wellbeing, and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team. For more detail on the benefits we offer at Agios, visit the Inside Agios section of our website.
• Competitive and equitable performance-based compensation. This includes base salary and both short- and long-term incentives that are connected to our business strategy and vary based on individual and company performance.
• The current base salary range for this position is expected to be between $183,549 and $230,312 annualized; final salary will be determined based on various factors including, but not limited to, years of relevant experience, job knowledge, skills and proficiency, degree/education, and internal comparators.
• Psychological safety. We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries.
• Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We’re continuously looking to improve the inclusivity of our workforce.
• Commitment to community. We’re an active participant in the communities that surround us – the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked.

Interested in learning more about what makes our culture unique? Visit the Inside Agios section of our website.