Director, Site & CMC Programs – Strategy & Execution

Biopharma Careers; Indianapolis (IN); On-site; USD 203,000 - 246,000; Full time

Benefits offered by this job

Health Coverage

401(k) plan

Paid Time Off

Stock opportunities

Job summary

RayzeBio in Indianapolis is seeking a Director, Site and CMC Program Management to provide strategic leadership for end-to-end CMC programs and site operations. You will shape governance, enable cross-functional collaboration, and drive portfolio delivery to support oncology radiopharmaceutical development.

The role requires 10+ years in pharma/biotech with PM/CMC experience, strong leadership, and the ability to align diverse teams toward patient-focused outcomes in a fast-paced environment.

Qualifications

• Bachelor’s degree in life sciences, chemistry, engineering, pharmaceutical sciences, business, or related discipline required; advanced degree preferred.
• Minimum of 10 years in pharma/biotech with significant program/CMC experience.
• Experience leading cross-functional, matrixed teams and complex programs.

Responsibilities

• Provide strategic leadership and operational oversight for Indianapolis site-based and end-to-end CMC programs.
• Build and lead the Program Management team; establish governance, KPIs, and reporting.
• Coordinate site and portfolio initiatives including manufacturing readiness, tech transfer, and supply chain planning.
• Identify risks and dependencies; drive mitigation and escalation as needed.
• Prepare concise updates and executive materials for governance forums.

Skills

Strategic leadership

Cross-functional leadership

Executive communication

Portfolio management

Problem solving

AI for program performance

Education

Bachelor's degree in life sciences/related

Advanced degree preferred

Job description

RayzeBio in Indianapolis is seeking a Director, Site and CMC Program Management to provide strategic leadership for end-to-end CMC programs and site operations. You will shape governance, enable cross-functional collaboration, and drive portfolio delivery to support oncology radiopharmaceutical development.

The role requires 10+ years in pharma/biotech with PM/CMC experience, strong leadership, and the ability to align diverse teams toward patient-focused outcomes in a fast-paced environment.