Director, Signal Detection Scientist

Scorpion Therapeutics; New Jersey; On-site; USD 140,000 - 200,000; Full time

Job summary

Scorpion Therapeutics is seeking a senior pharmacovigilance leader to drive lead signal detection activities for complex therapies from post-marketing data sources.

You will develop surveillance strategies, perform signal validation, and prepare safety analyses while communicating findings to safety teams and stakeholders. Travel up to 10% across US sites is expected as you mentor colleagues and guide cross-functional discussions on methodology.

Qualifications

• Advanced healthcare-related degree (e.g., RN, PharmD) with 9+ years in drug safety, including 3+ years in signal detection.
• Deep understanding of signal detection systems, global safety regulations, and data analysis tools (e.g., FDA AEMS, VigiBase).
• Experience with SAS JMP, epidemiologic principles, public health surveillance, and machine learning.

Responsibilities

• Develop and implement surveillance strategies.
• Perform signal validation.
• Prepare safety data analyses.
• Communicate findings to safety teams and stakeholders.
• Lead cross-functional discussions on signal evaluation, guide data source selection and analysis methods, and support exploration of novel safety surveillance methodologies.
• Provide mentorship and contribute to training efforts.

Skills

Signal detection

Leadership

Cross-functional

Communication

Mentorship

Education

RN

PharmD

Tools

FDA AEMS

VigiBase

SAS JMP

Job description

Role

Lead signal detection activities within pharmacovigilance for complex pharmaceutical products, focusing on proactive safety signal identification and evaluation from post-marketing data sources.

Responsibilities

• develop and implement surveillance strategies
• perform signal validation
• prepare safety data analyses
• communicate findings to safety teams and stakeholders
• Lead cross-functional discussions on signal evaluation, guide data source selection and analysis methods, and support exploration of novel safety surveillance methodologies.
• Provide mentorship and contribute to training efforts.

Requirements

advanced healthcare-related degree (e.g., RN, PharmD) with at least 9 years of industry experience in drug safety, including 3+ years in signal detection, and 1+ year of clinical/patient-care experience.

Deep understanding of signal detection systems, global safety regulations, and data analysis tools (e.g., FDA AEMS, VigiBase).

Preferred

experience with SAS JMP, epidemiologic principles, public health surveillance, and machine learning.

High-value biopharma specifics include focus on post-marketing safety surveillance for large innovative or complex products, with responsibilities spanning signal detection, validation, and methodology development.

Collaboration involves safety teams, medical officers, and global regulatory agencies.

Location

multiple US sites; travel up to 10%.

The role emphasizes scientific independence, leadership, and technological innovation in pharmacovigilance.