Director, Signal Detection Scientist

Scorpion Therapeutics; Horsham (PA); On-site; USD 180,000 - 240,000; Full time

Job summary

Johnson & Johnson Innovative Medicine seeks a Director, Signal Detection Scientist to lead proactive safety signal detection and evaluation for complex pharmaceutical products. Based in Horsham, PA, you will drive advanced analytics and collaborate with safety teams to strengthen pharmacovigilance practices.

You will develop surveillance strategies, utilize novel computational tools, and perform signal validation, contributing to safety assessments across global regulatory frameworks.

Qualifications

• Advanced healthcare degree (RN, PharmD) with 9+ years in pharmacovigilance or drug safety.
• 3+ years dedicated to signal detection.
• Clinical/patient-care experience.

Responsibilities

• Develop surveillance strategies and use computational tools for signal detection across data sources.
• Perform signal validation and communicate findings to safety teams and stakeholders.
• Conduct post-marketing aggregate safety data reviews and support methodologies for safety surveillance.

Skills

SAS JMP

Epidemiological principles

Machine learning

Public health tools

Education

Advanced healthcare degree (RN, PharmD)

Job description

Role

Director, Signal Detection Scientist leading proactive safety signal detection and evaluation for complex pharmaceutical products within Johnson & Johnson's Innovative Medicine division.

Responsibilities

• Develop and execute surveillance strategies, utilize novel computational tools for signal detection across multiple data sources (e.g., regulatory databases, claims, electronic health records), perform signal validation, and communicate findings to safety teams and stakeholders.
• Conduct post-marketing aggregate safety data reviews, contribute to safety assessments, and support the development of methodologies for safety surveillance.

Requirements

• Advanced healthcare degree (RN, PharmD) with 9+ years in pharmacovigilance or drug safety, including at least 3 years dedicated to signal detection.
• Clinical/patient-care experience.
• Deep understanding of safety data analysis, global regulatory guidance, and signal detection systems.

Preferred

• Experience with SAS JMP or similar platforms, epidemiological principles, machine learning, and public health tools.

Travel

Travel up to 10% domestically and internationally.

High-value specifics

Focus on post-marketing safety in innovative or complex therapeutic areas, leveraging advanced analytics and novel methodologies to enhance pharmacovigilance practices.