Medical Director, Safety Sciences

Denali Therapeutics; South San Francisco (CA); On-site; USD 250,000 - 360,000; Full time

Job summary

Scorpion Therapeutics seeks a senior medical safety leader to drive safety strategy across multiple clinical development programs. You will oversee signal detection, risk management, and regulatory submissions, guiding safety governance forums and mentoring a safety team.

The role requires MD or MD/PhD with 10+ years in drug safety, pharmacovigilance, or clinical development and comprehensive knowledge of global pharmacovigilance regulations, signal detection methodologies, and risk management.

Qualifications

• MD or MD/PhD required.
• 10+ years in drug safety, pharmacovigilance, or clinical development with progressively senior safety leadership experience.

Responsibilities

• Lead safety assessments across programs or therapeutic areas.
• Manage safety signal detection and risk management activities.
• Oversee safety reporting and regulatory submissions.
• Contribute to safety governance forums.
• Mentor safety team members.

Skills

Senior safety leadership

Pharmacovigilance

Global regulatory compliance

Education

MD

MD/PhD

Job description

Role

Provide senior medical safety leadership across multiple clinical development programs or a therapeutic area within biopharma, focusing on safety strategy, signal detection, and benefit–risk evaluation.

Responsibilities

• lead safety assessments
• manage safety signal detection and risk management activities
• oversee safety reporting and regulatory submissions
• contribute to safety governance forums
• mentor safety team members

Requirements

• MD or MD/PhD
• 10+ years in drug safety, pharmacovigilance, or clinical development with progressively senior safety leadership experience; strong knowledge of global pharmacovigilance regulations, signal detection methodologies, and safety risk management.

HighValue

• senior safety leadership
• pharmacovigilance
• global regulatory compliance
• complex safety assessments
• cross-functional influence

WorkSetup

• not specified, but likely office-based with potential for cross-functional collaboration.