Director, Research Informatics & AI-Driven Platforms

Denali-Therapeutics; South San Francisco (CA); On-site; USD 204,000 - 265,000; Full time

Benefits offered by this job

401k

Healthcare coverage

ESPP

Broad range of benefits

Job summary

Denali Therapeutics seeks a Director of Research Informatics to lead the strategy and execution of our scientific data platforms, including Benchling and Dotmatics, and to drive AI integration across experiments. You will build and mentor a high-caliber engineering team while partnering with Discovery, IT, and Operations.

Responsibilities include setting roadmaps, prioritizing work, and ensuring compliant, attributable records. Strong collaboration and hands-on platform work are required.

Qualifications

• Bachelor's degree in a technical field; advanced degree preferred.
• 10+ years building and delivering software solutions in pharma/biotech.
• 8+ years of people management experience, including building engineering teams.

Responsibilities

• Owns strategy, roadmap, and delivery of Research Informatics platforms and AI integration.
• Leads platform support, configuration, validation, and continuous improvement.
• Partners with scientists and IT to translate requirements into scalable solutions.
• Communicates platform strategy and risk to senior stakeholders clearly.
• Drives vendor relationships and platform migrations; hands-on configuration work.

Skills

Leadership

Stakeholder communication

ELN/data workflows understanding

Education

Bachelor's degree in technical field

Advanced degree preferred

Tools

Benchling

Dotmatics

AI integration

Job description

Denali Therapeutics seeks a Director of Research Informatics to lead the strategy and execution of our scientific data platforms, including Benchling and Dotmatics, and to drive AI integration across experiments. You will build and mentor a high-caliber engineering team while partnering with Discovery, IT, and Operations.

Responsibilities include setting roadmaps, prioritizing work, and ensuring compliant, attributable records. Strong collaboration and hands-on platform work are required.