Director of Statistical Genetics & Genomic Insights

Bristol Myers Squibb; Needham (MA); On-site; USD 240,000 - 291,000; Full time

Benefits offered by this job

Health Coverage

Wellbeing Programs

401(k) plan

Job summary

Bris­tol Myers Squibb (BMS) seeks a senior Statistical Genetics leader to drive causal mechanism discovery from human genetics. You will head the Target Sciences team within IPS, collaborating across discovery and translational efforts to align genetics insights with disease biology and drug target prioritization.

The role emphasizes integrating omics and large-scale genetic data, leading multi-disciplinary teams, and communicating findings through internal forums and external publications.

Qualifications

• PhD in statistical genetics or related field.
• 8+ years postdoctoral research and/or industry experience preferred.
• 6+ years leadership experience.
• Experience applying genetics to drug discovery.
• Advanced knowledge of GWAS, Mendelian randomization, colocalization, polygenic risk scores.
• Proficiency in R or Python.

Responsibilities

• Drive design and implementation of computational strategy to infer causal mechanisms driving disease using human genetics and other data types (e.g. Mendelian randomization with proteomics, TWAS, colocalization).
• Lead team to perform cross-biobank analyses focused on identifying mechanisms underlying human genetic risk factors (eQTL mapping, scRNAseq).
• Coordinate with stakeholders across research to enable discovery using germline genetics in neuro, immunology, and cardiovascular disease.
• Evaluate and prioritize multi-modal datasets to understand causal human biology of priority disease areas.
• Coordinate with stakeholders to nominate, evaluate, and advance novel drug targets.
• Communicate findings in meetings and external publications.

Skills

Leadership experience

R or Python programming

Statistical genetics

Genetics-to-drug-discovery

GWAS

Mendelian randomization

Colocalization

Polygenic risk scores

Multi-disciplinary team leadership

Functional genomics familiarity

Education

PhD in statistical genetics

Master's degree

Bachelor's degree

Tools

R

Python

Job description

Bris­tol Myers Squibb (BMS) seeks a senior Statistical Genetics leader to drive causal mechanism discovery from human genetics. You will head the Target Sciences team within IPS, collaborating across discovery and translational efforts to align genetics insights with disease biology and drug target prioritization.

The role emphasizes integrating omics and large-scale genetic data, leading multi-disciplinary teams, and communicating findings through internal forums and external publications.