Director of Portfolio & Program Strategy

Vertex Pharmaceuticals Incorporated; Boston (MA); Hybrid; USD 162,000 - 243,000; Full time

Benefits offered by this job

Hybrid-Eligible Work Model

Annual bonus eligibility

Equity awards

Job summary

Vertex Pharmaceuticals Incorporated is seeking a Director of Portfolio and Program Management to lead strategic and operational oversight across cross-functional research programs from early research through preclinical development. You will partner with the CGT Site Head and senior leadership to drive prioritization, governance, and delivery of site objectives.

The role emphasizes data-driven decision making, risk management, and development of PPM capabilities.

Qualifications

• Typically requires an advanced degree in Life Sciences or a relevant field (PhD preferred).
• 10+ years of experience with portfolio and program management in drug discovery or early development.

Responsibilities

• Lead portfolio planning and drive strategic decision-making across research and early development programs.
• Oversee a portfolio of Research programs from early research to candidate preclinical development.
• Manage cross-functional projects, ensuring milestones, governance, and resource alignment.
• Provide portfolio updates including status, risks, milestones, and decisions to site leadership.
• Develop and maintain integrated portfolio timelines and reporting, identifying bottlenecks and interdependencies.

Skills

Portfolio management

Cross-functional leadership

Strategic decision-making

Data-driven decision making

Executive communications

Education

Advanced degree in Life Sciences (PhD preferred)

Job description

Vertex Pharmaceuticals Incorporated is seeking a Director of Portfolio and Program Management to lead strategic and operational oversight across cross-functional research programs from early research through preclinical development. You will partner with the CGT Site Head and senior leadership to drive prioritization, governance, and delivery of site objectives.

The role emphasizes data-driven decision making, risk management, and development of PPM capabilities.