Director of Computational Biology Operations & Capabilities

Takeda; Boston (MA); On-site; USD 180,000 - 240,000; Full time

Job summary

Takeda is seeking an Associate Director/Director of Computational Biology Scientific Operations & Capability Lead to expand capabilities and excellence across GI2 programs. This role partners with clinical development, translational medicine, discovery, and DD&T teams to align external activities with priorities and portfolio needs.

The position emphasizes building scalable workflows, setting standards, and guiding external partnerships to ensure rigorous, reproducible analyses and

Qualifications

• PhD (or MS with significant industry experience) in Computational Biology, Bioinformatics, Systems Biology, Genomics, Data Science or a related discipline.
• 8+ years of relevant experience in pharmaceutical, biotechnology, CRO, FSP, or related life sciences organizations.
• Strong experience applying Computational Biology approaches to drug discovery, translational medicine, biomarker research, precision medicine, or clinical development.
• Demonstrated experience guiding complex multi-omics and translational data analyses.
• Experience interacting with external scientific partners, contractors, FSPs, CROs, or distributed scientific teams.
• Strong matrix leadership and stakeholder-management skills.
• Excellent written, verbal, and presentation skills.
• Proven ability to operate effectively across geographies, cultures, and time zones.

Responsibilities

• Serve as the primary scientific interface between the Boston-based Computational Biology team and India-based FSPs, contractors, and external partners.
• Translate GI2 scientific priorities into clear analytical plans, deliverables, and quality expectations.
• Oversee externally supported Computational Biology activities and reduce coordination and oversight burden on Boston-based scientists.
• Provide scientific leadership and oversight for Computational Biology analyses, ensuring outputs are rigorous, reproducible, and decision-ready.
• Apply expertise in computational biology, multi-omics, biomarkers, and translational research to guide analysis and interpretation.
• Build reusable Computational Biology workflows, standards, and best practices that can be applied across programs and disease areas.
• Advance scalable analytical capabilities through partnerships with Computational Biology, Digital, DD&T, and Data Science teams.
• Maintain targeted engagement with priority programs to ensure external execution remains aligned with scientific and portfolio priorities.
• Support program teams with insights related to biomarkers, disease biology, patient stratification, and multi-omics analysis.
• Foster a culture of scientific excellence, innovation, collaboration, and continuous improvement across internal and external teams.

Skills

Matrix leadership

Stakeholder management

Communication skills

External collaboration

Education

PhD in Computational Biology

MS with significant industry experience

Job description

Takeda is seeking an Associate Director/Director of Computational Biology Scientific Operations & Capability Lead to expand capabilities and excellence across GI2 programs. This role partners with clinical development, translational medicine, discovery, and DD&T teams to align external activities with priorities and portfolio needs.

The position emphasizes building scalable workflows, setting standards, and guiding external partnerships to ensure rigorous, reproducible analyses and