Associate Director, Computational Biology

Takeda; Boston (MA); On-site; USD 180,000 - 240,000; Full time

Job summary

Takeda is seeking an Associate Director/Director of Computational Biology Scientific Operations & Capability Lead to expand capabilities and excellence across GI2 programs. This role partners with clinical development, translational medicine, discovery, and DD&T teams to align external activities with priorities and portfolio needs.

The position emphasizes building scalable workflows, setting standards, and guiding external partnerships to ensure rigorous, reproducible analyses and

Qualifications

• PhD (or MS with significant industry experience) in Computational Biology, Bioinformatics, Systems Biology, Genomics, Data Science or a related discipline.
• 8+ years of relevant experience in pharmaceutical, biotechnology, CRO, FSP, or related life sciences organizations.
• Strong experience applying Computational Biology approaches to drug discovery, translational medicine, biomarker research, precision medicine, or clinical development.
• Demonstrated experience guiding complex multi-omics and translational data analyses.
• Experience interacting with external scientific partners, contractors, FSPs, CROs, or distributed scientific teams.
• Strong matrix leadership and stakeholder-management skills.
• Excellent written, verbal, and presentation skills.
• Proven ability to operate effectively across geographies, cultures, and time zones.

Responsibilities

• Serve as the primary scientific interface between the Boston-based Computational Biology team and India-based FSPs, contractors, and external partners.
• Translate GI2 scientific priorities into clear analytical plans, deliverables, and quality expectations.
• Oversee externally supported Computational Biology activities and reduce coordination and oversight burden on Boston-based scientists.
• Provide scientific leadership and oversight for Computational Biology analyses, ensuring outputs are rigorous, reproducible, and decision-ready.
• Apply expertise in computational biology, multi-omics, biomarkers, and translational research to guide analysis and interpretation.
• Build reusable Computational Biology workflows, standards, and best practices that can be applied across programs and disease areas.
• Advance scalable analytical capabilities through partnerships with Computational Biology, Digital, DD&T, and Data Science teams.
• Maintain targeted engagement with priority programs to ensure external execution remains aligned with scientific and portfolio priorities.
• Support program teams with insights related to biomarkers, disease biology, patient stratification, and multi-omics analysis.
• Foster a culture of scientific excellence, innovation, collaboration, and continuous improvement across internal and external teams.

Skills

Matrix leadership

Stakeholder management

Communication skills

External collaboration

Education

PhD in Computational Biology

MS with significant industry experience

Job description

Job Description

We have an exciting opportunity for an Associate Director / Director, Computational Biology Scientific Operations & Capability Lead to join the Computational Biology team within the Gastrointestinal & Inflammation Therapeutic Area Unit (GI2-TAU).

We are looking for:

• A scientific leader who will play a pivotal role in expanding Computational Biology capabilities and scientific impact across GI2 programs through high-quality external scientific execution, reusable analytical capabilities, and operational excellence.
• An expert in computational biology and translational bioinformatics with deep experience in multi-omics analysis, biomarker research, and AI/ML-enabled analytical approaches, capable of guiding and critically evaluating complex scientific analyses.
• A strategic collaborator who will partner with clinical development, translational medicine, discovery, and DD&T teams to ensure externally supported Computational Biology activities remain aligned with program priorities and portfolio needs.
• A capability builder and innovator who will establish scalable workflows, scientific standards, and best practices that improve consistency, quality, & reproducibility across Computational Biology activities.
• A scientific operations leader who will serve as the primary interface between the Boston-based Computational Biology team and India-based FSPs, contractors, and external scientific partners, reducing communication, coordination, and oversight burden while strengthening execution quality across the network.

ACCOUNTABILITIES (Describe the primary duties and responsibilities of the job. Include only the essential functions of the job. Approximately 5-10 bulleted task statements should be identified.)

Scientific Operations & External Execution

• Serve as the primary scientific interface between the Boston-based Computational Biology team and India-based FSPs, contractors, and external partners.
• Translate GI2 scientific priorities into clear analytical plans, deliverables, and quality expectations.
• Oversee externally supported Computational Biology activities and reduce coordination and oversight burden on Boston-based scientists.

Scientific Leadership & Quality

• Provide scientific leadership and oversight for Computational Biology analyses, ensuring outputs are rigorous, reproducible, and decision-ready.
• Apply expertise in computational biology, multi-omics, biomarkers, and translational research to guide analysis and interpretation.

Capability Development

• Build reusable Computational Biology workflows, standards, and best practices that can be applied across programs and disease areas.
• Advance scalable analytical capabilities through partnerships with Computational Biology, Digital, DD&T, and Data Science teams.

Program Support & Collaboration

• Maintain targeted engagement with priority programs to ensure external execution remains aligned with scientific and portfolio priorities.
• Support program teams with insights related to biomarkers, disease biology, patient stratification, and multi-omics analysis.
• Foster a culture of scientific excellence, innovation, collaboration, and continuous improvement across internal and external teams.

Technical/Functional (Line) Expertise

• Deep expertise in Computational Biology, Bioinformatics, Systems Biology, Translational Bioinformatics, or related disciplines.
• Strong background in multi-omics analysis, biomarker discovery, patient stratification, and translational data analysis.
• Experience applying advanced analytical approaches, including AI/ML methods, to support decision-making.
• Ability to review, challenge, and guide complex scientific analyses and biological interpretations.
• Strong understanding of reproducible research practices, data quality standards, and analytical governance.

Leadership

• Provide scientific leadership across internal and external teams within a matrix environment.
• Influence scientific strategy, operating models, and capability development initiatives.
• Drive alignment among diverse stakeholders with competing priorities.
• Build trust and credibility with scientific leaders, program teams, and external partners.

Decision-making and Autonomy

• Operate independently with broad accountability for quality and effectiveness of external Computational Biology execution.
• Make informed decisions regarding analytical approaches, prioritization, quality standards, and risk mitigation.
• Provide recommendations that influence program decisions, capability investments, and operational strategy.

Interaction

• Collaborate across Computational Biology, Translational Medicine, Clinical Development, Discovery, Biomarker Sciences, and DD&T functions.
• Engage regularly with FSPs, contractors, CROs, academic collaborators, and technology partners.
• Communicate complex scientific concepts effectively to technical and non-technical audiences.

Innovation

• Drive adoption of scalable analytical approaches and reusable Computational Biology capabilities.
• Champion continuous improvement, operational excellence, and knowledge sharing.
• Evaluate emerging technologies and identify opportunities to enhance scientific execution and efficiency.

Complexity

• TBD/Not applicable

EDUCATION, BEHAVIOURAL COMPETENCIES AND SKILLS:

Required

• PhD (or MS with significant industry experience) in Computational Biology, Bioinformatics, Systems Biology, Genomics, Data Science or a related discipline.
• 8+ years of relevant experience in pharmaceutical, biotechnology, CRO, FSP, or related life sciences organizations.
• Strong experience applying Computational Biology approaches to drug discovery, translational medicine, biomarker research, precision medicine, or clinical development.
• Demonstrated experience guiding complex multi-omics and translational data analyses.
• Experience interacting with external scientific partners, contractors, FSPs, CROs, or distributed scientific teams.
• Strong matrix leadership and stakeholder-management skills.
• Excellent written, verbal, and presentation skills.
• Proven ability to operate effectively across geographies, cultures, and time zones.

Preferred

• Experience in immunology, gastroenterology, inflammation, rare disease related therapeutic areas.
• Experience supporting clinical-stage programs, biomarker strategies, and translational research initiatives.
• Experience building reusable analytical workflows, standards, or capability platforms.
• Familiarity with cloud-based analytical environments, FAIR data principles, and enterprise data platforms.
• Experience mentoring Computational Biologists, Bioinformaticians, Data Scientists, or scientific teams.
• Experience operating within global matrix organizations.

Locations

IND - Bengaluru - Research and Development

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time