Director Medical Affairs

Accordance Search Group; New Jersey; On-site; USD 240,000 - 360,000; Full time

Job summary

Accordance Search Group is seeking a senior Medical Affairs Director / Senior Director to lead Medical Affairs for a solid tumor portfolio in a key regional market, aligning clinical strategy with commercial goals. This role anchors the medical roadmap, oversees evidence generation, RWE/HEOR programs, and collaborates with Global R&D and Commercial teams to inform development decisions.

Ideal candidate brings extensive oncology medical affairs leadership, cross-functional collaboration, and

Responsibilities

• Act as the clinical authority for the regional market, integrating insights into global strategies.
• Lead the medical matrix team and cross-functional partnerships to shape medical plans.
• Drive annual and long-range medical planning and execution across the portfolio.
• Oversee evidence generation programs, including RWE, HEOR, and post-marketing studies.

Job description

Title: Medical Affairs Director / Senior Director – Solid Tumor & Pipeline Strategy

Overview of the Role

We are seeking a senior clinical and strategic leader to direct Medical Affairs for a high-priority therapeutic portfolio. This position anchors the strategic medical roadmap for a commercialized solid tumor indication while simultaneously guiding early-stage oncology assets transitioning from early development into late-stage planning.

Reporting to executive leadership within the Oncology therapeutic area, you will serve as the primary clinical authority for a key regional market. This role blends high-level portfolio strategy with hands-on execution. You will ensure that regional healthcare landscape nuances, patient needs, and clinical insights are structurally integrated into global development strategies and executive portfolio decision-making.

Key Focus Areas & Strategic Responsibilities

• Global to Regional Clinical Interface: Act as the vital link between Medical Affairs, Global R&D, Early/Clinical Development, and Commercialization teams. You will ensure local market insights are clearly understood and integrated by global asset teams, commercial committees, and executive governance boards.
• Commercial Portfolio Leadership: Serve as the medical subject matter expert for an established commercial solid tumor therapy. You will collaborate with cross-functional partners to build, align, and execute comprehensive medical strategies and regional evidence plans.
• Early-Stage Pipeline Influence: Partner closely with early clinical development teams to evaluate future treatment paradigms. You will help shape clinical development pathways, data generation strategies, and target product profiles (TPPs) for early-stage oncology assets, using the regional therapeutic landscape as a primary strategic framework.

Core Functions

• Cross-Functional Leadership: Head the dedicated medical matrix team for the therapeutic area's primary commercial asset.
• Long-Range Planning: Drive the creation, alignment, and execution of annual and long-range medical plans.
• Evidence & Data Generation: Direct comprehensive evidence generation frameworks, overseeing real-world evidence (RWE) programs, health outcomes research (HEOR), investigator-initiated studies, and post-marketing clinical trials.