Director Medical Affairs

Accordance Search Group; California; On-site; USD 180,000 - 280,000; Full time

Job summary

Accordance Search Group is seeking a Medical Affairs Director/Senior Director to lead a solid tumor portfolio in California. The role combines strategic medical leadership with execution across global to regional interfaces, shaping evidence plans and clinical development input for later-stage assets.

You will partner with R&D, Commercial, and HEOR teams to align regional insights with global strategies, drive long-range medical plans, and oversee RWE and investigator-initiated studies to

Responsibilities

• Global to regional clinical interface; ensure local insights are integrated into global asset teams and governance boards.
• Lead medical strategies and regional evidence plans for an established solid tumor therapy.
• Influence early-stage pipeline by shaping development pathways and TPPS using regional landscape.
• Oversee cross-functional medical matrix team and long-range medical plans.
• Direct evidence generation programs including real-world evidence and HEOR.

Job description

Title: Medical Affairs Director / Senior Director – Solid Tumor & Pipeline Strategy

Overview of the Role

We are seeking a senior clinical and strategic leader to direct Medical Affairs for a high-priority therapeutic portfolio. This position anchors the strategic medical roadmap for a commercialized solid tumor indication while simultaneously guiding early-stage oncology assets transitioning from early development into late-stage planning.

Reporting to executive leadership within the Oncology therapeutic area, you will serve as the primary clinical authority for a key regional market. This role blends high-level portfolio strategy with hands-on execution. You will ensure that regional healthcare landscape nuances, patient needs, and clinical insights are structurally integrated into global development strategies and executive portfolio decision-making.

Key Focus Areas & Strategic Responsibilities

• Global to Regional Clinical Interface: Act as the vital link between Medical Affairs, Global R&D, Early/Clinical Development, and Commercialization teams. You will ensure local market insights are clearly understood and integrated by global asset teams, commercial committees, and executive governance boards.
• Commercial Portfolio Leadership: Serve as the medical subject matter expert for an established commercial solid tumor therapy. You will collaborate with cross-functional partners to build, align, and execute comprehensive medical strategies and regional evidence plans.
• Early-Stage Pipeline Influence: Partner closely with early clinical development teams to evaluate future treatment paradigms. You will help shape clinical development pathways, data generation strategies, and target product profiles (TPPs) for early-stage oncology assets, using the regional therapeutic landscape as a primary strategic framework.

Core Functions

• Cross-Functional Leadership: Head the dedicated medical matrix team for the therapeutic area's primary commercial asset.
• Long-Range Planning: Drive the creation, alignment, and execution of annual and long-range medical plans.
• Evidence & Data Generation: Direct comprehensive evidence generation frameworks, overseeing real-world evidence (RWE) programs, health outcomes research (HEOR), investigator-initiated studies, and post-marketing clinical trials.