Director, Direct-to-Patient Market Transformation

Vertex Pharmaceuticals Incorporated; Boston (MA); Hybrid; USD 196,000 - 294,000; Full time

Job summary

Vertex Pharmaceuticals Incorporated is seeking a strategic, execution-focused Director, Market Transformation to design and implement direct-to-patient capabilities across the patient journey. You will optimize diagnosis and treatment access, reduce friction and drive measurable conversions through end‑to‑end patient pathways.

The role requires deep biopharma commercialization experience, strong knowledge of access and support models, and the ability to translate strategy into scalable

Qualifications

• 8+ years in biopharma, healthcare, digital health or patient services.
• 5+ years leadership in patient access, commercialization, patient support, digital health, market access or omnichannel engagement.
• Experience designing or scaling patient-centric programs across multiple stages of the patient journey.
• Strong understanding of pharmaceutical commercialization and reimbursement dynamics.
• Experience building business cases, operating models and strategic roadmaps for new capabilities.
• Proven success leading complex cross-functional initiatives.
• Strong analytical and problem-solving skills with data-driven recommendations.
• Excellent executive communication and presentation skills.

Responsibilities

• Develop Vertex's direct-to-patient strategy across brands and therapy areas to improve access.
• Monitor market trends and competitor activity to inform strategy.
• Identify patient drop-off points across diagnosis, referral, reimbursement and therapy initiation.
• Design and optimize end-to-end patient pathways including activation and adherence.
• Build business cases for DTP investments with ROI measurement.
• Define and implement DTP models such as journey orchestration and direct commerce.
• Partner across functions to connect patient touchpoints into a seamless experience.
• Establish governance and KPIs across brand, access, digital, and patient support teams.
• Lead development of scalable enterprise capabilities across the portfolio.
• Oversee external partnerships and vendor strategy for telehealth, pharmacy and digital engagement.
• Drive innovation in patient engagement including education and retargeting.
• Ensure all DTP initiatives align with legal, regulatory and privacy standards.

Skills

Patient journey mapping

DTP engagement strategy

Access and reimbursement strategy

Digital health strategy

Cross-functional leadership

Strategic roadmaps

Data analytics

Education

Bachelor's degree

Tools

CRM systems

EHR / HIE workflows

Job description

Vertex Pharmaceuticals Incorporated is seeking a strategic, execution-focused Director, Market Transformation to design and implement direct-to-patient capabilities across the patient journey. You will optimize diagnosis and treatment access, reduce friction and drive measurable conversions through end‑to‑end patient pathways.

The role requires deep biopharma commercialization experience, strong knowledge of access and support models, and the ability to translate strategy into scalable