Director, Clinical Pharmacology & Pharmacometrics (Remote)

Scorpion Therapeutics; Waltham (MA); On-site; USD 140,000 - 210,000; Full time

Benefits offered by this job

Remote work

Job summary

Scorpion Therapeutics is seeking an Associate Director of Clinical Pharmacology & Pharmacometrics to lead quantitative modeling efforts for autoimmune/inflammatory and neuromuscular portfolios. You will inform dose selection for FIH and Phase 2 trials, support bridging formulations, and contribute to regulatory submissions.

In this role, you will collaborate across Clinical Development, Research, Regulatory, and CMC, and present complex results to leadership and regulators.

Qualifications

• Ph.D. in Pharmacometrics, Clinical Pharmacology, or related field.
• 6–8 years industry experience with hands-on modeling in MATLAB (SimBiology), NONMEM, and R.
• Expertise in translating nonclinical/clinical data into human dose strategies.
• Strong communication skills.

Responsibilities

• Develop and apply quantitative models (QSP, PopPK, E-R) to inform dose selection in FIH and Phase 2.
• Support formulation bridging and regulatory submissions.
• Collaborate across Clinical Development, Research, Regulatory, and CMC functions.
• Present findings to leadership and regulatory agencies.

Skills

Modeling (QSP, PopPK, E-R)

MATLAB SimBiology

NONMEM

R

Dose strategy translation

Communication skills

Education

PhD in Pharmacometrics or Clinical Pharmacology

Tools

MATLAB

NONMEM

R

Job description

Scorpion Therapeutics is seeking an Associate Director of Clinical Pharmacology & Pharmacometrics to lead quantitative modeling efforts for autoimmune/inflammatory and neuromuscular portfolios. You will inform dose selection for FIH and Phase 2 trials, support bridging formulations, and contribute to regulatory submissions.

In this role, you will collaborate across Clinical Development, Research, Regulatory, and CMC, and present complex results to leadership and regulators.