Deputy Director Manufacturing Operations

Sanofi EU; Pearl River (NY); On-site; USD 180,000 - 240,000; Full time

Benefits offered by this job

Health benefits

Parental leave (14 weeks)

Career growth opportunities

Global mobility

Job summary

Sanofi US Services in Pearl River, NY seeks a Deputy Director of Manufacturing Operations to lead multi-site manufacturing activities, ensuring readiness, quality, and compliance across upstream and downstream processes.

You will mentor leaders, optimize production schedules, drive continuous improvement, and partner with QA, Regulatory, and cross-functional teams to deliver lifecycle-ready processes and a robust supply chain.

Qualifications

• Bachelor’s degree in engineering, science, life sciences, business, or related field.
• 5-7 years of pharmaceutical or biopharmaceutical manufacturing experience.
• 5+ years of progressive, hands-on leadership in GMP manufacturing.
• Strong GMP/GDP knowledge and application.
• Proven Lean manufacturing expertise (5S, Gemba, Daily Capacity).
• Root cause analysis on manufacturing deviations and corrective actions.
• Experience with performance management routines (+QDCI or similar).
• Strong conflict management and decision-making in fast-paced settings.
• Excellent communication and stakeholder management.
• Understanding of cell growth in biopharma manufacturing.

Responsibilities

• Lead safety and high-performance culture across manufacturing teams.
• Direct upstream/downstream operations including cell culture and purification.
• Oversee production schedules meeting output targets with compliance.
• Ensure readiness of equipment, materials, and documentation before production.
• Drive GMP/GDP compliance and deviation investigations with RCA.
• Lead cross-functional collaboration with Process Development, Quality, Supply Chain, and Engineering.

Skills

Leadership

GMP/GDP knowledge

Lean manufacturing

Root cause analysis

Quality management

Cross-functional collaboration

People management

Education

Bachelor’s degree in engineering/science/life sciences or related field

Tools

Single Use Systems

Chromatography

Tangential Flow Filtration

Stainless Steel Systems

Job description

Job Title: Deputy Director Manufacturing Operations

Location: Pearl River, NY

About the Job

Join a global network that powers how Sanofi delivers — seamlessly, purposefully, and at scale. In Manufacturing & Supply, you’ll help reimagine how life-changing treatments reach people everywhere, faster.

About Sanofi:

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve lives.

Main Responsibilities

Leadership & Team Management

• Ensure all areas and employees are safe at all times

• Directly manage manufacturing teams supporting upstream and downstream Flublok drug substance operations

• Foster a high-performance culture grounded in accountability, collaboration, and continuous improvement

• Provide coaching, mentorship, and professional development to team members at all levels

• Effectively manage conflict within and across teams to maintain a productive and respectful work environment

• Drive a strong sense of urgency in day-to-day operations while maintaining quality and compliance standards

Manufacturing Readiness & Operations

• Ensure manufacturing areas are consistently ready for scheduled production activities

• Oversee upstream and downstream manufacturing processes, including cell culture, protein production, clarification, purification, and related unit operations

• Monitor and manage production schedules to meet output targets while maintaining compliance with all applicable standards

• Ensure all equipment, materials, documentation, and personnel are in a state of readiness prior to manufacturing execution

Quality, Compliance & Continuous Improvement

• Ensure all manufacturing activities are conducted in strict accordance with GMP (Good Manufacturing Practice) and GDP (Good Documentation Practice) requirements

• Lead and support deviation investigations, applying structured root cause analysis (RCA) methodologies to identify, document, and resolve manufacturing deviations

• Champion Lean manufacturing principles and defect identification practices to eliminate waste and drive process efficiency

• Implement and sustain performance management routines, including +QDCI (Quality, Delivery, Cost, Involvement) metrics and visual management tools

• Partner with Quality Assurance and Regulatory Affairs to support inspections, audits, and regulatory submissions as needed

Strategic & Cross-Functional Collaboration

• Collaborate with Process Development, Quality, Supply Chain, and Engineering teams to support technology transfers, process improvements, and capacity planning

• Represent manufacturing in cross-functional forums and contribute to site-level strategic initiatives

• Identify and elevate risks to manufacturing readiness, supply continuity, or compliance in a timely manner

• Support the development and management of departmental budgets and resource planning

About You

Basic Qualifications

• Bachelor’s degree in engineering, Science, Life Sciences, Business, or any related field.

• 5 -7 years of experience in pharmaceutical or biopharmaceutical manufacturing.

• 5+ years of Progressive, hands‑on leadership experience in a GMP manufacturing environment, with an expectation to interact with and solve problems at the shop floor level.

• Strong working knowledge of GMP and GDP regulations and their application in a manufacturing environment

• Proven expertise in Lean manufacturing methodologies (5s, Gemba Problem Solving, Daily Capacity Management) and defect identification/reduction.

• Demonstrated ability to perform thorough root cause analysis on manufacturing deviations and implement effective corrective actions.

• Experience with performance management routines, including +QDCI or equivalent operational excellence frameworks.

• Strong conflict management skills with the ability to navigate interpersonal and team dynamics effectively.

• Demonstrated sense of urgency and ability to prioritize and respond decisively in a fast-paced manufacturing environment

• Excellent communication, organizational, and stakeholder management skills

• Understanding of cell growth and propagation principles as they apply to biopharmaceutical drug substance manufacturing

Preferred Qualifications

• Advanced degree (MS, MBA) in Life Sciences, Engineering, Business Administration or related technical field.

• Hands‑on experience with one or more of the following technologies:

  • Single Use Systems

  • Chromatography

  • Tangential Flow Filtration

  • Stainless Steel Systems (Fermenters and Bioreactors)

Why choose us?

• Bring the miracles of science to life alongside a supportive, future-focused team.

• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention andwellness programs and at least 14 weeks’ gender-neutral parental leave.

• Shape the future of medicine and vaccine delivery with cutting‑edge technology, ensuring seamless launches and a resilient global supply.

• Power industry‑leading performance by leveraging digital, data, and AI-driven innovation – at speed and scale

• Transform lives worldwide by delivering life‑changing treatments anywhere, anytime.

Sanofi US Services and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.