Data Scientist / Biostatistician

Jefferies; New York (NY); On-site; USD 135,000 - 165,000; Full time

Benefits offered by this job

Health insurance

Job summary

Jefferies is seeking a Data Scientist / Biostatistician to join its AI-driven biotech and pharma equity research team in New York. The role focuses on building proprietary AI, machine-learning, and statistical models to predict clinical-trial outcomes and generate differentiated investment insights.

The candidate will analyze trial design, powering and endpoints while leveraging NLP and generative AI to process publications, regulatory documents, and earnings calls.

Qualifications

• PhD, MD, or master’s degree preferred in biostatistics, statistics, data science, AI, epidemiology, bioinformatics or related fields.
• Strong Python or R skills and experience building ML, predictive, or generative-AI models.
• Solid knowledge of clinical-trial design and statistical analysis.
• Ability to explain complex quantitative findings clearly.
• Interest in biotechnology, drug development, investing and financial markets.

Responsibilities

• Build AI and statistical models to predict clinical-trial outcomes, regulatory results and commercial potential.
• Analyze trial design, endpoints, powering, populations, treatment effects, safety and subgroups.
• Use generative AI, LLMs and NLP to analyze publications, regulatory docs, trial registries, disclosures and earnings calls.
• Create automated tools to track pipelines, catalysts, competitive programs and risks.
• Translate model outputs and clinical data into clear investment conclusions.
• Collaborate with research analysts on forecasts, pipeline valuations and published research.
• Validate models and control bias, overfitting, data leakage and AI hallucinations.

Skills

Python

R

Machine learning

Generative AI

Statistical analysis

Communication of findings

Education

PhD/MD/Master's preferred

Job description

AI-Driven Biotech & Pharma Equity Research

We are seeking a Data Scientist / Biostatistician to join our biotech and pharmaceutical equity research team. The role will focus on building proprietary AI, machine-learning, and statistical models to predict clinical-trial outcomes and generate differentiated investment insights.

Responsibilities

• Build AI and statistical models to predict clinical-trial results, probability of success, regulatory outcomes, and commercial potential.
• Analyze trial design, endpoints, powering, patient populations, treatment effects, safety, and subgroup data.
• Use generative AI, LLMs, and natural-language processing to analyze scientific publications, regulatory documents, trial registries, company disclosures, and earnings transcripts.
• Create automated tools to track pipelines, clinical catalysts, competitive programs, and emerging risks.
• Convert model outputs and clinical data into clear investment conclusions.
• Work with research analysts on company forecasts, pipeline valuations, and published research.
• Validate models and control for bias, overfitting, data leakage, and AI hallucinations.

Qualifications

• PhD, MD, or master’s degree preferred in biostatistics, statistics, data science, artificial intelligence, epidemiology, bioinformatics, computational biology, medicine, or a related field.
• Strong Python or R skills.
• Experience building machine-learning, predictive, or generative-AI models.
• Strong knowledge of clinical-trial design and statistical analysis.
• Ability to explain complex scientific and quantitative findings clearly.
• Interest in biotechnology, drug development, investing, and financial markets.
• Equity-research experience is helpful but not required.

Primary Location Full Time Salary Range of $135,000 - $165,000.

About Us

Jefferies is a leading global, full-service investment banking and capital markets firm that provides advisory, sales and trading, research, and wealth and asset management services. With more than 40 offices around the world, we offer insights and expertise to investors, companies, and governments.

At Jefferies, we are committed to building a culture that provides opportunities for all employees regardless of our differences and supports a workforce that is reflective of the communities where we work and live. As a result, we are able to pool our collective insights and intelligence to provide fresh and innovative thinking for our clients.

Jefferies is committed to creating and sustaining a workforce that welcomes individuals from all backgrounds to apply. Our employment decisions are made without regard to race, creed, color, national origin, ancestry, religion, pregnancy, age, medical condition, physical or mental disability, marital status, domestic partner status, sex, sexual orientation, gender, gender identity or expression, veteran or military status, genetic information, reproductive health decisions, or any other factor protected by applicable law. We are committed to hiring the most qualified applicants and complying with all federal, state, and local equal employment opportunity laws. As part of this commitment, Jefferies will extend reasonable accommodation to individuals with disabilities, as required by applicable law.

The salary offered will take into consideration an individual’s experience level and qualifications. In addition to salary, Jefferies Financial Group is proud to offer a comprehensive benefits package to eligible, full-time employees or part-time employees, who are scheduled to work at least 30 hours or more per week, including an annual discretionary incentive and retention bonus, competitive employee benefits, including: medical, dental & vision coverage; 401(k); life, accident, and disability insurance; and wellness programs. Jefferies also offers paid time off packages that include planned time off (e.g., vacation), unplanned time off (e.g., sick leave), and paid holidays, and for full-time employees, paid parental leave.