Cryo-EM Scientist: Collaborative Microscopy & Imaging

Socket.dev; Hamilton (MT); On-site; USD 90,000 - 110,000; Full time

Benefits offered by this job

Medical, Dental & Vision Coverage for

Paid Time Off and Paid Holidays

401K match up to 5%

Educational Benefits for Career Growth

Employee Referral Bonus

Flexible Spending Accounts: Healthcare

Parking Reimbursement Account

Dependent Care Assistant Program

Transportation Reimbursement Account

Job summary

Axle is a bioscience and information technology company located in Hamilton, Montana, recruiting a cryo-electron microscopist to support infectious disease research in the Rocky Mountain Laboratories. This hands-on role emphasizes cryo-EM, room-temperature EM, and advanced techniques like CLEM and FIB-SEM, working with scientists across multiple groups.

Based in Hamilton, MT, the role collaborates with NIH investigators, maintains records, trains staff, and contributes to lab operations while

Qualifications

• Master’s degree or higher in a relevant field (Cell Biology, Structural Biology, Biophysics, or similar).
• Solid understanding of EM sample preparation and imaging workflows.

Responsibilities

• Perform negative staining on purified proteins to evaluate sample quality.
• Prepare biological samples for cryo-EM (plunge freezing) and perform imaging and analysis.
• Operate and help maintain TEM and other ancillary instruments, including troubleshooting when needed.
• Work closely with NIAID investigators to plan experiments, interpret results, and solve technical challenges.
• Help bring new capabilities online, including techniques like CLEM, FIB-SEM, and cryo-EM.
• Keep clear, well‑organized records in line with NIH standards for rigor and reproducibility.
• Train and support other lab members or facility users in EM techniques and image processing.
• Contribute to the overall operation of the lab, including equipment upkeep and safety compliance.

Skills

Cryo-EM

Image analysis

Team collaboration

Detail-oriented

Education

Master's degree in Cell Biology/Structural Biology/Biophysics

Tools

TEM

FIB-SEM

CLEM

Job description

Axle is a bioscience and information technology company located in Hamilton, Montana, recruiting a cryo-electron microscopist to support infectious disease research in the Rocky Mountain Laboratories. This hands-on role emphasizes cryo-EM, room-temperature EM, and advanced techniques like CLEM and FIB-SEM, working with scientists across multiple groups.

Based in Hamilton, MT, the role collaborates with NIH investigators, maintains records, trains staff, and contributes to lab operations while