Cryo-EM Scientist: Advanced Imaging, CLEM & FIB-SEM

Axle Info; Hamilton, Northern (MT, KY); Hybrid; USD 90,000 - 110,000; Full time

Benefits offered by this job

Paid Time Off

Paid Holidays

401K match up to 5%

Educational Benefits for Career Growth

Employee Referral Bonus

Flexible Spending Accounts

Healthcare (FSA)

Parking Reimbursement Account (PRK)

Dependent Care Assistant Program (DCAP

Transportation Reimbursement Account (

Transportation Reimbursement Account (

Job summary

Axle is seeking a skilled Cryo-electron microscopist for the Research Technologies Branch (RTB), Electron Microscopy Unit (EMU) in Hamilton, MT. This hands-on role focuses on cryo-EM data generation to support infectious disease research with NIH investigators.

You will work with room-temperature EM techniques and help implement new capabilities while maintaining thorough records and training colleagues.

Qualifications

• Master's degree or higher in a relevant field.
• Solid understanding of EM sample prep and imaging workflows.
• Experience operating and troubleshooting EM instruments.
• Communication and collaboration across multiple projects.

Responsibilities

• Perform negative staining on purified proteins to evaluate sample quality.
• Prepare biological samples for cryo-EM (plunge freezing) and perform imaging and analysis.
• Operate and help maintain TEM and other ancillary instruments, including troubleshooting when needed.
• Work closely with investigators to plan experiments, interpret results, and solve technical challenges.
• Help bring new capabilities online, including CLEM, FIB-SEM, and cryo-EM.
• Keep clear, well-organized records in NIH standards for rigor and reproducibility.
• Train and support lab members in EM techniques and image processing.
• Contribute to lab operations, including equipment upkeep and safety compliance.

Skills

EM sample prep

Imaging workflows

EM instrument troubleshooting

Collaborative team player

Education

Master's degree or higher

Tools

Cryo-EM instruments

TEM

FIB-SEM

Job description

Axle is seeking a skilled Cryo-electron microscopist for the Research Technologies Branch (RTB), Electron Microscopy Unit (EMU) in Hamilton, MT. This hands-on role focuses on cryo-EM data generation to support infectious disease research with NIH investigators.

You will work with room-temperature EM techniques and help implement new capabilities while maintaining thorough records and training colleagues.