Cryo-EM Research Scientist: Imaging & Innovation

Axle; Hamilton (MT); On-site; USD 90,000 - 110,000; Full time

Benefits offered by this job

Paid Time Off and Paid Holidays

401K match up to 5%

Educational Benefits for Career Growth

Employee Referral Bonus

Flexible Spending Accounts

Healthcare (FSA)

Parking Reimbursement Account (PRK)

Dependent Care Assistant Program (DCAP

Transportation Reimbursement Account (

Transportation Reimbursement Account (

Job summary

Axle in Hamilton, MT seeks a Cryo-electron microscopist to join the RTB, EM Unit at Rocky Mountain Laboratories. The role focuses on generating high-quality EM data to support infectious disease research and involves hands-on work with cryo-EM and related techniques.

The position emphasizes collaboration across research groups, room-temperature EM exploration, and maintaining NIH-style rigorous records. Strong emphasis on teamwork and data integrity in a fast-paced lab.

Qualifications

• Master's degree or higher in a relevant field.
• Solid understanding of EM sample preparation and imaging workflows.
• Experience operating EM instruments.
• Strong communication and collaborative abilities.

Responsibilities

• Perform negative staining on purified proteins to evaluate sample quality.
• Prepare biological samples for cryo-EM (plunge freezing) and perform imaging and analysis.
• Operate and help maintain TEM and other ancillary instruments, including troubleshooting when needed.
• Work closely with NIAID investigators to plan experiments, interpret results, and solve technical challenges.
• Help bring new capabilities online, including techniques like CLEM, FIB-SEM, and cryo-EM.
• Keep clear, well-organized records in line with NIH standards for rigor and reproducibility.
• Train and support other lab members or facility users in EM techniques and image processing.
• Contribute to the overall operation of the lab, including equipment upkeep and safety compliance.

Skills

EM sample prep

EM imaging workflows

TEM operation

Team collaboration

Education

Master's degree or higher in Cell Biology / Structural Biology / Biophysics

Tools

CLEM tools

FIB-SEM hardware

Image analysis software

Job description

Axle in Hamilton, MT seeks a Cryo-electron microscopist to join the RTB, EM Unit at Rocky Mountain Laboratories. The role focuses on generating high-quality EM data to support infectious disease research and involves hands-on work with cryo-EM and related techniques.

The position emphasizes collaboration across research groups, room-temperature EM exploration, and maintaining NIH-style rigorous records. Strong emphasis on teamwork and data integrity in a fast-paced lab.