Computational Sensing Scientist (Nanopore & ML)

Socket.dev; Cambridge (MA); On-site; USD 120,000 - 170,000; Full time

Job summary

Tilde Bio, Inc. seeks a Bioinformatics Scientist to join our Computational Team to connect nanopore measurements to biological understanding. You will work directly with experimental scientists and engineers to develop methods that transform complex biological measurements into actionable scientific insight.

This role requires creating and implementing standard pipelines, and goes beyond them. Here, you will build fundamental approaches to understanding and processing electronic data into an

Qualifications

• Master's degree + 3+ years of industry experience or PhD in Computational Biology, Biophysics, Bioengineering, Physics, Applied Mathematics, Computer Science, Electrical Engineering, or related quantitative discipline.
• Strong programming skills in Python and scientific computing environments.
• Experience analyzing complex biological, physical, or time-series datasets — particularly with noise and experimental variability.
• Solid background in at least two of: statistics, machine learning, signal processing, or Bayesian modeling.
• Comfortable working across experimental and computational domains; able to engage with wet-lab scientists on data interpretation.
• Clear scientific communicator — written and verbal.

Responsibilities

• Analyze nanopore and electrophysiology datasets to identify biologically meaningful signal features.
• Develop and implement computational workflows for event detection, classification, and molecular fingerprinting.
• Build quantitative models that connect nanopore measurements to molecular identity, structure, and function.
• Collaborate with experimental scientists to interpret results and shape future experiments.
• Partner with protein science, signal processing, and machine learning teams to improve platform performance and analytical capabilities.
• Help establish best practices for benchmarking, validation, and uncertainty quantification as the platform scales.

Skills

Python

Data analysis

Statistics

Machine learning

Signal processing

Bayesian modeling

Interdisciplinary collaboration

Education

Master's degree + 3+ years industry experience

PhD in Computational Biology/Biophysics/Bioengineering/Physics/Applied Mathematics/CS/EE

Job description

Tilde Bio, Inc. seeks a Bioinformatics Scientist to join our Computational Team to connect nanopore measurements to biological understanding. You will work directly with experimental scientists and engineers to develop methods that transform complex biological measurements into actionable scientific insight.

This role requires creating and implementing standard pipelines, and goes beyond them. Here, you will build fundamental approaches to understanding and processing electronic data into an