Commercial Supply Chain Director, Cell & Gene Therapy

Vertex Pharmaceuticals; Boston (MA); Hybrid; USD 176,000 - 264,000; Full time

Job summary

An established industry player is seeking a Commercial Supply Chain Director to spearhead the management strategy for cutting-edge cell and gene therapies. This pivotal role involves optimizing operations, ensuring regulatory compliance, and driving cross-functional collaboration to enhance patient scheduling and manufacturing capacity. The ideal candidate will possess extensive experience in supply chain management and a deep understanding of pharmaceutical regulations. Join a forward-thinking organization committed to innovation and excellence in the biotechnology sector, where your expertise will help shape the future of therapeutic solutions.

Benefits

Medical, dental, and vision benefits

Generous paid time off

Educational assistance programs

Student loan repayment

Commuting subsidy

401(k) matching

Annual bonus and equity awards

Qualifications

• 10+ years of experience in Manufacturing and Supply Chain Management.
• Strong analytical and problem-solving skills with advanced judgment.

Responsibilities

• Lead slot management strategy and operations for cell and gene therapy.
• Drive creation and usage of KPIs Dashboard for business decisions.

Skills

Manufacturing and Supply Chain Management

Analytical Skills

Project Management

Regulatory Knowledge (cGMP, GCP, GDP)

Communication Skills

Education

Bachelor's degree in a scientific or business discipline

Tools

ERP/MRP systems

Oracle OPM

Job description

Commercial Supply Chain Director, Cell & Gene Therapy

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Commercial Supply Chain Director, Cell & Gene Therapy

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Join to apply for the Commercial Supply Chain Director, Cell & Gene Therapy role at Vertex Pharmaceuticals

Job Description

The Director of Cell and Gene Therapy Commercial Supply Chain will lead the slot management strategy, development, and operations to support Vertex’s autologous cell and gene therapy program. The slot management model includes dynamic, short range, and situational planning and operations to allow visibility and patient scheduling. The Director will also be responsible for establishing, maintaining, revising, and executing slot management rules and principles to ensure patients are appropriately scheduled within manufacturing capacity and regulatory requirements. This includes chairing steering committee meetings and key presentations to cross-functional leaders. Through cross-functional alignment, the Director will drive the creation, maintenance, and usage of a Key Performance Indicators (KPIs) Dashboard. These KPIs will be used proactively to drive business decisions, lend insight into business analytics, and create process improvement opportunities. In this role, the Director will be responsible for creating business processes and opportunities to ensure capacity utilization across the Supply Chain network. This includes representation as key Supply Chain lead for cross-functional workstream and initiatives. The Director will work closely with key stakeholders including the Strategic Product Lead, Finance, Regulatory, Commercial, Logistics, Manufacturing, and Vertex’s Cell and Gene Therapy Site.

Summary

Job Description

The Director of Cell and Gene Therapy Commercial Supply Chain will lead the slot management strategy, development, and operations to support Vertex’s autologous cell and gene therapy program. The slot management model includes dynamic, short range, and situational planning and operations to allow visibility and patient scheduling. The Director will also be responsible for establishing, maintaining, revising, and executing slot management rules and principles to ensure patients are appropriately scheduled within manufacturing capacity and regulatory requirements. This includes chairing steering committee meetings and key presentations to cross-functional leaders. Through cross-functional alignment, the Director will drive the creation, maintenance, and usage of a Key Performance Indicators (KPIs) Dashboard. These KPIs will be used proactively to drive business decisions, lend insight into business analytics, and create process improvement opportunities. In this role, the Director will be responsible for creating business processes and opportunities to ensure capacity utilization across the Supply Chain network. This includes representation as key Supply Chain lead for cross-functional workstream and initiatives. The Director will work closely with key stakeholders including the Strategic Product Lead, Finance, Regulatory, Commercial, Logistics, Manufacturing, and Vertex’s Cell and Gene Therapy Site.

The Director will establish operating principles with Vertex’s Cell and Gene Therapy program to ensure robust communication and alignment for slot management, scheduling, and KPIs/Business Analytics. This role will play an integral part in the commercialization and scalability of Vertex’s Cell and Gene Therapy assets.

Key Responsibilities

• Interacts with senior level management
• Conducts executive level presentations on critical supply chain issues, initiatives, and projects.
• Designs and implements functional/department goals and participates in setting goals for Commercial Manufacturing and Supply Chain (CMSC)
• Serve as key contributor on company-wide initiatives
• Integrate and advance KPI modeling to inform and make business decisions.
• Drive system requirements, compliance, testing, and utilization to meet the needs of patients.
• Identify and implement new processes and capabilities needed to support Cell and Gene Therapy programs.
• Collaborate and align with Strategic Program Lead (SPL) to lead and track program-specific deliverables
• Anticipate future industry trends and keep abreast with a strong foundational of knowledge of manufacturing, development, and supply
  
  

Minimal Requirements

• Bachelor's degree in a scientific or business discipline preferred, or equivalent years of relevant experience
• Typically requires 10+ years of experience in Manufacturing and Supply Chain Management
• Demonstrated ability to successfully plan and optimize all resources of an area (budgets, staff, technology, etc.) for advancement of all goals and objectives
• Ability to apply complex judgement and advanced analytical thought to develop novel/innovative solutions
• Strong overall business acumen and understanding of the industry and business drivers
• Highly specialized depth of knowledge on regulations relating to pharmaceutical supply chain activities (cGMP, GCP, GDP, import/export, computer systems/Part 11) as well as ERP/MRP systems, Oracle OPM
• Exceptional analytical and problem-solving skills, often addressing novel/unusual situations and exercising complex judgement based on significant technical experience and interpretive thinking
• Drives effective, productive business relationships across the function and the organization
• Highly skilled in managing customer, stakeholder or leadership expectations, communicating in complex or sensitive situations, facilitating mutually beneficial outcomes and influencing/guiding others to adopt a new point of view; skilled negotiator, able to resolve complex problems
• Strong experience in building and managing high-performing teams
  
  

#SV-1

Pay Range

$176,000 - $264,000

Disclosure Statement

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status

In this Hybrid-Eligible role, you can choose to be designated as:

• Hybrid: work remotely up to two days per week; or select
• On-Site: work five days per week on-site with ad hoc flexibility.
  
  

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [e-mail]

Seniority level

• Seniority level

  Director

Employment type

• Employment type

  Full-time

Job function

• Job function

  Management and Manufacturing

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