CMC Pipeline Innovation Scientist II (Cell Therapy)

Merck & Co.; New Jersey; On-site; USD 111,000 - 145,000; Full time

Benefits offered by this job

Medical, dental, vision insurance

401(k) with company match

Paid parental leave

Paid time off

Job summary

Legend Biotech in the United States seeks a Scientist II, CMC Pipeline Innovation to advance manufacturing, analytical, and characterization technologies for cell and gene therapies. The role focuses on hands-on execution of studies to improve process understanding, product quality, and scalability across development pipelines.

You will collaborate with cross-functional teams, communicate innovation outcomes, and transfer successful technologies into development and manufacturing workflows, with

Qualifications

• PhD in Biology, Biomedical Engineering, Virology, Immunology, or related field; 0–3 years preferred, or MS/BS with equivalent experience.
• Strong hands-on experience with bioprocess unit operations (bioreactors, TFF, sterile filtration, chromatography).
• Experience with LVV processes and analytical tools desirable but not required.

Responsibilities

• Execute LVV downstream process development including capture and polishing strategies.
• Develop proof-of-concept, feasibility, and characterization studies.
• Design experiments to evaluate new technologies for improved process understanding and quality.

Skills

LVV processing

Bioprocess engineering

Data analysis

Laboratory skills

Education

PhD or MS/BS in Biology/Engineering/Immunology

Tools

HPLC

UHPLC

LC-MS/MS

GraphPad Prism

Job description

Legend Biotech in the United States seeks a Scientist II, CMC Pipeline Innovation to advance manufacturing, analytical, and characterization technologies for cell and gene therapies. The role focuses on hands-on execution of studies to improve process understanding, product quality, and scalability across development pipelines.

You will collaborate with cross-functional teams, communicate innovation outcomes, and transfer successful technologies into development and manufacturing workflows, with